Anti-SRB4D/ SSC4D/ S4D-SRCRB functional antibody

Anti-SRB4D/ SSC4D/ S4D-SRCRB functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SSC4D/SSC4D products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1323-Ab-1/ GM-Tg-hg-SE1323-Ab-2Anti-Human SSC4D monoclonal antibodyHuman
GM-Tg-rg-SE1323-Ab-1/ GM-Tg-rg-SE1323-Ab-2Anti-Rat SSC4D monoclonal antibodyRat
GM-Tg-mg-SE1323-Ab-1/ GM-Tg-mg-SE1323-Ab-2Anti-Mouse SSC4D monoclonal antibodyMouse
GM-Tg-cynog-SE1323-Ab-1/ GM-Tg-cynog-SE1323-Ab-2Anti-Cynomolgus/ Rhesus macaque SSC4D monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1323-Ab-1/ GM-Tg-felg-SE1323-Ab-2Anti-Feline SSC4D monoclonal antibodyFeline
GM-Tg-cang-SE1323-Ab-1/ GM-Tg-cang-SE1323-Ab-2Anti-Canine SSC4D monoclonal antibodyCanine
GM-Tg-bovg-SE1323-Ab-1/ GM-Tg-bovg-SE1323-Ab-2Anti-Bovine SSC4D monoclonal antibodyBovine
GM-Tg-equg-SE1323-Ab-1/ GM-Tg-equg-SE1323-Ab-2Anti-Equine SSC4D monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1323-Ab-1/ GM-Tg-hg-SE1323-Ab-2; GM-Tg-rg-SE1323-Ab-1/ GM-Tg-rg-SE1323-Ab-2;
GM-Tg-mg-SE1323-Ab-1/ GM-Tg-mg-SE1323-Ab-2; GM-Tg-cynog-SE1323-Ab-1/ GM-Tg-cynog-SE1323-Ab-2;
GM-Tg-felg-SE1323-Ab-1/ GM-Tg-felg-SE1323-Ab-2; GM-Tg-cang-SE1323-Ab-1/ GM-Tg-cang-SE1323-Ab-2;
GM-Tg-bovg-SE1323-Ab-1/ GM-Tg-bovg-SE1323-Ab-2; GM-Tg-equg-SE1323-Ab-1/ GM-Tg-equg-SE1323-Ab-2
Products NameAnti-SSC4D monoclonal antibody
Formatmab
Target NameSSC4D
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SSC4D benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1323-Ag-1Recombinant multi-species SRB4D/ SSC4D/ S4D-SRCRB protein


    Target information

    Target IDGM-SE1323
    Target NameSSC4D
    Gene ID136853,109267,304401,100430867,608018,101091673,539182,100060975
    Gene Symbol and SynonymsC330016E03Rik,S4D-SRCRB,SRCRB-S4D,SRCRB4D,SSC4D
    Uniprot AccessionQ8WTU2
    Uniprot Entry NameSRB4D_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000146700
    Target ClassificationN/A

    The target: SSC4D, gene name: SSC4D, also named as S4D-SRCRB, SRCRB-S4D, SRCRB4D. The scavenger receptor cysteine-rich (SRCR) superfamily is an ancient and highly conserved group of cell surface and/or secreted proteins, some of which are involved in the development of the immune system and the regulation of both innate and adaptive immune responses. Group B SRCR domains usually contain 8 regularly spaced cysteines that give rise to a well-defined intradomain disulfide-bond pattern.[supplied by OMIM, Apr 2004].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.