- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-1433S/ SFN/ YWHAS functional antibody
Anti-1433S/ SFN/ YWHAS functional antibody for cell culture, ELISA & in-vivo assay
Go to SFN/SFN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1283-Ab-1/ GM-Tg-hg-SE1283-Ab-2 | Anti-Human SFN monoclonal antibody | Human |
| GM-Tg-rg-SE1283-Ab-1/ GM-Tg-rg-SE1283-Ab-2 | Anti-Rat SFN monoclonal antibody | Rat |
| GM-Tg-mg-SE1283-Ab-1/ GM-Tg-mg-SE1283-Ab-2 | Anti-Mouse SFN monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1283-Ab-1/ GM-Tg-cynog-SE1283-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SFN monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1283-Ab-1/ GM-Tg-felg-SE1283-Ab-2 | Anti-Feline SFN monoclonal antibody | Feline |
| GM-Tg-cang-SE1283-Ab-1/ GM-Tg-cang-SE1283-Ab-2 | Anti-Canine SFN monoclonal antibody | Canine |
| GM-Tg-bovg-SE1283-Ab-1/ GM-Tg-bovg-SE1283-Ab-2 | Anti-Bovine SFN monoclonal antibody | Bovine |
| GM-Tg-equg-SE1283-Ab-1/ GM-Tg-equg-SE1283-Ab-2 | Anti-Equine SFN monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1283-Ab-1/ GM-Tg-hg-SE1283-Ab-2; GM-Tg-rg-SE1283-Ab-1/ GM-Tg-rg-SE1283-Ab-2; GM-Tg-mg-SE1283-Ab-1/ GM-Tg-mg-SE1283-Ab-2; GM-Tg-cynog-SE1283-Ab-1/ GM-Tg-cynog-SE1283-Ab-2; GM-Tg-felg-SE1283-Ab-1/ GM-Tg-felg-SE1283-Ab-2; GM-Tg-cang-SE1283-Ab-1/ GM-Tg-cang-SE1283-Ab-2; GM-Tg-bovg-SE1283-Ab-1/ GM-Tg-bovg-SE1283-Ab-2; GM-Tg-equg-SE1283-Ab-1/ GM-Tg-equg-SE1283-Ab-2 |
| Products Name | Anti-SFN monoclonal antibody |
| Format | mab |
| Target Name | SFN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SFN benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1283-Ag-1 | Recombinant multi-species 1433S/ SFN/ YWHAS protein |
| ORF Viral Vector | pGMLP002188 | human SFN Lentivirus plasmid |
| ORF Viral Vector | vGMLP002188 | human SFN Lentivirus particle |
| ORF Viral Vector | pGMLPm001220 | mouse Sfn Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001220 | mouse Sfn Lentivirus particle |
Target information
| Target ID | GM-SE1283 |
| Target Name | SFN |
| Gene ID | 2810,55948,313017,715055,487351,101087501,528453,100057082 |
| Gene Symbol and Synonyms | 14-3-3,Er,Mme1,SFN,YWHAS |
| Uniprot Accession | P31947,Q0VC36 |
| Uniprot Entry Name | 1433S_HUMAN,1433S_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000175793 |
| Target Classification | N/A |
The target: SFN, gene name: SFN, also named as YWHAS. This gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis. [provided by RefSeq, Aug 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
