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Anti-NEUT/ NTS/ NMN-125 functional antibody
Anti-NEUT/ NTS/ NMN-125 functional antibody for cell culture, ELISA & in-vivo assay
Go to NTS/NTS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1140-Ab-1/ GM-Tg-hg-SE1140-Ab-2 | Anti-Human NTS monoclonal antibody | Human |
| GM-Tg-rg-SE1140-Ab-1/ GM-Tg-rg-SE1140-Ab-2 | Anti-Rat NTS monoclonal antibody | Rat |
| GM-Tg-mg-SE1140-Ab-1/ GM-Tg-mg-SE1140-Ab-2 | Anti-Mouse NTS monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1140-Ab-1/ GM-Tg-cynog-SE1140-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NTS monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1140-Ab-1/ GM-Tg-felg-SE1140-Ab-2 | Anti-Feline NTS monoclonal antibody | Feline |
| GM-Tg-cang-SE1140-Ab-1/ GM-Tg-cang-SE1140-Ab-2 | Anti-Canine NTS monoclonal antibody | Canine |
| GM-Tg-bovg-SE1140-Ab-1/ GM-Tg-bovg-SE1140-Ab-2 | Anti-Bovine NTS monoclonal antibody | Bovine |
| GM-Tg-equg-SE1140-Ab-1/ GM-Tg-equg-SE1140-Ab-2 | Anti-Equine NTS monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1140-Ab-1/ GM-Tg-hg-SE1140-Ab-2; GM-Tg-rg-SE1140-Ab-1/ GM-Tg-rg-SE1140-Ab-2; GM-Tg-mg-SE1140-Ab-1/ GM-Tg-mg-SE1140-Ab-2; GM-Tg-cynog-SE1140-Ab-1/ GM-Tg-cynog-SE1140-Ab-2; GM-Tg-felg-SE1140-Ab-1/ GM-Tg-felg-SE1140-Ab-2; GM-Tg-cang-SE1140-Ab-1/ GM-Tg-cang-SE1140-Ab-2; GM-Tg-bovg-SE1140-Ab-1/ GM-Tg-bovg-SE1140-Ab-2; GM-Tg-equg-SE1140-Ab-1/ GM-Tg-equg-SE1140-Ab-2 |
| Products Name | Anti-NTS monoclonal antibody |
| Format | mab |
| Target Name | NTS |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-NTS benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1140-Ag-1 | Recombinant multi-species NEUT/ NTS/ NMN-125 protein |
| ORF Viral Vector | vGMAP000426 | Human NTS Adenovirus particle |
| ORF Viral Vector | vGMLP000544 | human NTS Lentivirus particle |
| ORF Viral Vector | pGMLP000544 | human NTS Lentivirus plasmid |
| ORF Viral Vector | pGMAP000426 | Human NTS Adenovirus plasmid |
| ORF Viral Vector | pGMLPm000714 | mouse Nts Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000714 | mouse Nts Lentivirus particle |
Target information
| Target ID | GM-SE1140 |
| Target Name | NTS |
| Gene ID | 4922,67405,299757,700189,611687,101095835,280881,100062225 |
| Gene Symbol and Synonyms | 5033428E16Rik,NMN-125,NN,NT,NT/N,NTS,NTS1 |
| Uniprot Accession | P30990,P20068,P10673,P01156 |
| Uniprot Entry Name | NEUT_HUMAN,NEUT_RAT,NEUT_CANLF,NEUT_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000133636 |
| Target Classification | N/A |
The target: NTS, gene name: NTS, also named as NMN-125, NN, NT, NT/N1, NTS. This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Oct 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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