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Anti-KCP/ CRIM21/ NET67 functional antibody
Anti-KCP/ CRIM21/ NET67 functional antibody for cell culture, ELISA & in-vivo assay
Go to KCP/KCP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1045-Ab-1/ GM-Tg-hg-SE1045-Ab-2 | Anti-Human KCP monoclonal antibody | Human |
| GM-Tg-rg-SE1045-Ab-1/ GM-Tg-rg-SE1045-Ab-2 | Anti-Rat KCP monoclonal antibody | Rat |
| GM-Tg-mg-SE1045-Ab-1/ GM-Tg-mg-SE1045-Ab-2 | Anti-Mouse KCP monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1045-Ab-1/ GM-Tg-cynog-SE1045-Ab-2 | Anti-Cynomolgus/ Rhesus macaque KCP monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1045-Ab-1/ GM-Tg-felg-SE1045-Ab-2 | Anti-Feline KCP monoclonal antibody | Feline |
| GM-Tg-cang-SE1045-Ab-1/ GM-Tg-cang-SE1045-Ab-2 | Anti-Canine KCP monoclonal antibody | Canine |
| GM-Tg-bovg-SE1045-Ab-1/ GM-Tg-bovg-SE1045-Ab-2 | Anti-Bovine KCP monoclonal antibody | Bovine |
| GM-Tg-equg-SE1045-Ab-1/ GM-Tg-equg-SE1045-Ab-2 | Anti-Equine KCP monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1045-Ab-1/ GM-Tg-hg-SE1045-Ab-2; GM-Tg-rg-SE1045-Ab-1/ GM-Tg-rg-SE1045-Ab-2; GM-Tg-mg-SE1045-Ab-1/ GM-Tg-mg-SE1045-Ab-2; GM-Tg-cynog-SE1045-Ab-1/ GM-Tg-cynog-SE1045-Ab-2; GM-Tg-felg-SE1045-Ab-1/ GM-Tg-felg-SE1045-Ab-2; GM-Tg-cang-SE1045-Ab-1/ GM-Tg-cang-SE1045-Ab-2; GM-Tg-bovg-SE1045-Ab-1/ GM-Tg-bovg-SE1045-Ab-2; GM-Tg-equg-SE1045-Ab-1/ GM-Tg-equg-SE1045-Ab-2 |
| Products Name | Anti-KCP monoclonal antibody |
| Format | mab |
| Target Name | KCP |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-KCP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1045-Ag-1 | Recombinant multi-species KCP/ CRIM21/ NET67 protein |
Target information
| Target ID | GM-SE1045 |
| Target Name | KCP |
| Gene ID | 375616,333088,296952,100428120,515624,100071778 |
| Gene Symbol and Synonyms | CRIM-2,CRIM2,Gm793,KCP,KCP-1,KCP1,NET67,RGD1561119 |
| Uniprot Accession | Q6ZWJ8 |
| Uniprot Entry Name | KCP_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | Ovary Cancer |
| Gene Ensembl | ENSG00000135253 |
| Target Classification | N/A |
The target: KCP, gene name: KCP, also named as CRIM21, NET67, KCP. Predicted to act upstream of or within hematopoietic progenitor cell differentiation and positive regulation of BMP signaling pathway. Predicted to be located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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