Anti-ITIH6/ ITIH5L/ UNQ6369 functional antibody

Anti-ITIH6/ ITIH5L/ UNQ6369 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ITIH6/ITIH6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1042-Ab-1/ GM-Tg-hg-SE1042-Ab-2Anti-Human ITIH6 monoclonal antibodyHuman
GM-Tg-rg-SE1042-Ab-1/ GM-Tg-rg-SE1042-Ab-2Anti-Rat ITIH6 monoclonal antibodyRat
GM-Tg-mg-SE1042-Ab-1/ GM-Tg-mg-SE1042-Ab-2Anti-Mouse ITIH6 monoclonal antibodyMouse
GM-Tg-cynog-SE1042-Ab-1/ GM-Tg-cynog-SE1042-Ab-2Anti-Cynomolgus/ Rhesus macaque ITIH6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1042-Ab-1/ GM-Tg-felg-SE1042-Ab-2Anti-Feline ITIH6 monoclonal antibodyFeline
GM-Tg-cang-SE1042-Ab-1/ GM-Tg-cang-SE1042-Ab-2Anti-Canine ITIH6 monoclonal antibodyCanine
GM-Tg-bovg-SE1042-Ab-1/ GM-Tg-bovg-SE1042-Ab-2Anti-Bovine ITIH6 monoclonal antibodyBovine
GM-Tg-equg-SE1042-Ab-1/ GM-Tg-equg-SE1042-Ab-2Anti-Equine ITIH6 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1042-Ab-1/ GM-Tg-hg-SE1042-Ab-2; GM-Tg-rg-SE1042-Ab-1/ GM-Tg-rg-SE1042-Ab-2;
GM-Tg-mg-SE1042-Ab-1/ GM-Tg-mg-SE1042-Ab-2; GM-Tg-cynog-SE1042-Ab-1/ GM-Tg-cynog-SE1042-Ab-2;
GM-Tg-felg-SE1042-Ab-1/ GM-Tg-felg-SE1042-Ab-2; GM-Tg-cang-SE1042-Ab-1/ GM-Tg-cang-SE1042-Ab-2;
GM-Tg-bovg-SE1042-Ab-1/ GM-Tg-bovg-SE1042-Ab-2; GM-Tg-equg-SE1042-Ab-1/ GM-Tg-equg-SE1042-Ab-2
Products NameAnti-ITIH6 monoclonal antibody
Formatmab
Target NameITIH6
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ITIH6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1042-Ag-1Recombinant multi-species ITIH6/ ITIH5L/ UNQ6369 protein


    Target information

    Target IDGM-SE1042
    Target NameITIH6
    Gene ID347365,634882,317416,701602,100337257,100062313
    Gene Symbol and SynonymsdJ14O9.1,Gm386,ITIH5L,Itih5l-ps,ITIH6,UNQ6369
    Uniprot AccessionQ6UXX5
    Uniprot Entry NameITIH6_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000102313
    Target ClassificationN/A

    The target: ITIH6, gene name: ITIH6, also named as ITIH5L, UNQ6369, dJ14O9.1. The protein encoded by this gene belongs to the interalpha trypsin inhibitor heavy chain (ITIH) family. Interalpha trypsin inhibitor (ITI) is composed of two heavy chains (containing VWA domain) and one light chain. The light chain confers the protease-inhibitor function, while the heavy chains are involved in mediating protein-protein interactions with the components of the extracellular matrix. [provided by RefSeq, Sep 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.