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Anti-HABP2/ FSAP/ HABP functional antibody
Anti-HABP2/ FSAP/ HABP functional antibody for cell culture, ELISA & in-vivo assay
Go to HABP2/HABP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0962-Ab-1/ GM-Tg-hg-SE0962-Ab-2 | Anti-Human HABP2 monoclonal antibody | Human |
| GM-Tg-rg-SE0962-Ab-1/ GM-Tg-rg-SE0962-Ab-2 | Anti-Rat HABP2 monoclonal antibody | Rat |
| GM-Tg-mg-SE0962-Ab-1/ GM-Tg-mg-SE0962-Ab-2 | Anti-Mouse HABP2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0962-Ab-1/ GM-Tg-cynog-SE0962-Ab-2 | Anti-Cynomolgus/ Rhesus macaque HABP2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0962-Ab-1/ GM-Tg-felg-SE0962-Ab-2 | Anti-Feline HABP2 monoclonal antibody | Feline |
| GM-Tg-cang-SE0962-Ab-1/ GM-Tg-cang-SE0962-Ab-2 | Anti-Canine HABP2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0962-Ab-1/ GM-Tg-bovg-SE0962-Ab-2 | Anti-Bovine HABP2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0962-Ab-1/ GM-Tg-equg-SE0962-Ab-2 | Anti-Equine HABP2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0962-Ab-1/ GM-Tg-hg-SE0962-Ab-2; GM-Tg-rg-SE0962-Ab-1/ GM-Tg-rg-SE0962-Ab-2; GM-Tg-mg-SE0962-Ab-1/ GM-Tg-mg-SE0962-Ab-2; GM-Tg-cynog-SE0962-Ab-1/ GM-Tg-cynog-SE0962-Ab-2; GM-Tg-felg-SE0962-Ab-1/ GM-Tg-felg-SE0962-Ab-2; GM-Tg-cang-SE0962-Ab-1/ GM-Tg-cang-SE0962-Ab-2; GM-Tg-bovg-SE0962-Ab-1/ GM-Tg-bovg-SE0962-Ab-2; GM-Tg-equg-SE0962-Ab-1/ GM-Tg-equg-SE0962-Ab-2 |
| Products Name | Anti-HABP2 monoclonal antibody |
| Format | mab |
| Target Name | HABP2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Diagnostic target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-HABP2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0962-Ag-1 | Recombinant multi-species HABP2/ FSAP/ HABP protein |
| ORF Viral Vector | pGMLP002112 | human HABP2 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002112 | human HABP2 Lentivirus particle |
| ORF Viral Vector | pGMLPm002699 | mouse Habp2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002699 | mouse Habp2 Lentivirus particle |
Target information
| Target ID | GM-SE0962 |
| Target Name | HABP2 |
| Gene ID | 3026,226243,292126,697495,477822,101080665,507993,100068293 |
| Gene Symbol and Synonyms | FSAP,HABP,HABP2,HGFAL,NMTC5,PHBP |
| Uniprot Accession | Q14520,Q6L711,Q5E9Z2 |
| Uniprot Entry Name | HABP2_HUMAN,HABP2_RAT,HABP2_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Diagnostics Biomarker |
| Disease | N/A |
| Gene Ensembl | ENSG00000148702 |
| Target Classification | N/A |
The target: HABP2, gene name: HABP2, also named as FSAP, HABP, HGFAL, NMTC5, PHBP. This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This extracellular protease binds hyaluronic acid and may play a role in the coagulation and fibrinolysis systems. Mutations in this gene are associated with nonmedullary thyroid cancer and susceptibility to venous thromboembolism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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