- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-VTDB/ GC/ DBP functional antibody
Anti-VTDB/ GC/ DBP functional antibody for cell culture, ELISA & in-vivo assay
Go to GC/GC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0937-Ab-1/ GM-Tg-hg-SE0937-Ab-2 | Anti-Human GC monoclonal antibody | Human |
| GM-Tg-rg-SE0937-Ab-1/ GM-Tg-rg-SE0937-Ab-2 | Anti-Rat GC monoclonal antibody | Rat |
| GM-Tg-mg-SE0937-Ab-1/ GM-Tg-mg-SE0937-Ab-2 | Anti-Mouse GC monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0937-Ab-1/ GM-Tg-cynog-SE0937-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GC monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0937-Ab-1/ GM-Tg-felg-SE0937-Ab-2 | Anti-Feline GC monoclonal antibody | Feline |
| GM-Tg-cang-SE0937-Ab-1/ GM-Tg-cang-SE0937-Ab-2 | Anti-Canine GC monoclonal antibody | Canine |
| GM-Tg-bovg-SE0937-Ab-1/ GM-Tg-bovg-SE0937-Ab-2 | Anti-Bovine GC monoclonal antibody | Bovine |
| GM-Tg-equg-SE0937-Ab-1/ GM-Tg-equg-SE0937-Ab-2 | Anti-Equine GC monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0937-Ab-1/ GM-Tg-hg-SE0937-Ab-2; GM-Tg-rg-SE0937-Ab-1/ GM-Tg-rg-SE0937-Ab-2; GM-Tg-mg-SE0937-Ab-1/ GM-Tg-mg-SE0937-Ab-2; GM-Tg-cynog-SE0937-Ab-1/ GM-Tg-cynog-SE0937-Ab-2; GM-Tg-felg-SE0937-Ab-1/ GM-Tg-felg-SE0937-Ab-2; GM-Tg-cang-SE0937-Ab-1/ GM-Tg-cang-SE0937-Ab-2; GM-Tg-bovg-SE0937-Ab-1/ GM-Tg-bovg-SE0937-Ab-2; GM-Tg-equg-SE0937-Ab-1/ GM-Tg-equg-SE0937-Ab-2 |
| Products Name | Anti-GC monoclonal antibody |
| Format | mab |
| Target Name | GC |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Diagnostic target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-GC benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0937-Ag-1 | Recombinant multi-species VTDB/ GC/ DBP protein |
| ORF Viral Vector | vGMLP003766 | human GC Lentivirus particle |
| ORF Viral Vector | pGMLP003766 | human GC Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001541 | mouse Gc Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001541 | mouse Gc Lentivirus particle |
Target information
| Target ID | GM-SE0937 |
| Target Name | GC |
| Gene ID | 2638,14473,24384,705708,475172,101096313,530076,100054939 |
| Gene Symbol and Synonyms | DBP,DBP-maf,DBP/GC,DBP02,GC,Gc-MAF,GcMAF,GRD3,HEL-S-51,VDB,VDBG,VDBP |
| Uniprot Accession | P02774,P04276,Q3MHN5 |
| Uniprot Entry Name | VTDB_HUMAN,VTDB_RAT,VTDB_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Diagnostics Biomarker |
| Disease | Sepsis |
| Gene Ensembl | ENSG00000145321 |
| Target Classification | N/A |
The target: GC, gene name: GC, also named as DBP, DBP-maf, DBP/GC, GRD3, Gc-MAF, GcMAF, HEL-S-51, VDB, VDBG, VDBP. The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
