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Anti-FGFP3/ FGFBP3/ C10orf13 functional antibody
Anti-FGFP3/ FGFBP3/ C10orf13 functional antibody for cell culture, ELISA & in-vivo assay
Go to FGFBP3/FGFBP3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0925-Ab-1/ GM-Tg-hg-SE0925-Ab-2 | Anti-Human FGFBP3 monoclonal antibody | Human |
| GM-Tg-rg-SE0925-Ab-1/ GM-Tg-rg-SE0925-Ab-2 | Anti-Rat FGFBP3 monoclonal antibody | Rat |
| GM-Tg-mg-SE0925-Ab-1/ GM-Tg-mg-SE0925-Ab-2 | Anti-Mouse FGFBP3 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0925-Ab-1/ GM-Tg-cynog-SE0925-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FGFBP3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0925-Ab-1/ GM-Tg-felg-SE0925-Ab-2 | Anti-Feline FGFBP3 monoclonal antibody | Feline |
| GM-Tg-cang-SE0925-Ab-1/ GM-Tg-cang-SE0925-Ab-2 | Anti-Canine FGFBP3 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0925-Ab-1/ GM-Tg-bovg-SE0925-Ab-2 | Anti-Bovine FGFBP3 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0925-Ab-1/ GM-Tg-equg-SE0925-Ab-2 | Anti-Equine FGFBP3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0925-Ab-1/ GM-Tg-hg-SE0925-Ab-2; GM-Tg-rg-SE0925-Ab-1/ GM-Tg-rg-SE0925-Ab-2; GM-Tg-mg-SE0925-Ab-1/ GM-Tg-mg-SE0925-Ab-2; GM-Tg-cynog-SE0925-Ab-1/ GM-Tg-cynog-SE0925-Ab-2; GM-Tg-felg-SE0925-Ab-1/ GM-Tg-felg-SE0925-Ab-2; GM-Tg-cang-SE0925-Ab-1/ GM-Tg-cang-SE0925-Ab-2; GM-Tg-bovg-SE0925-Ab-1/ GM-Tg-bovg-SE0925-Ab-2; GM-Tg-equg-SE0925-Ab-1/ GM-Tg-equg-SE0925-Ab-2 |
| Products Name | Anti-FGFBP3 monoclonal antibody |
| Format | mab |
| Target Name | FGFBP3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FGFBP3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0925-Ag-1 | Recombinant multi-species FGFP3/ FGFBP3/ C10orf13 protein |
| Cytokine | GM-Tg-g-SE0925-Ag-1 | fibroblast growth factor binding protein 3 (FGFBP3) protein |
Target information
| Target ID | GM-SE0925 |
| Target Name | FGFBP3 |
| Gene ID | 143282,72514,499349,697881,100855624,111557110,615980,100071367 |
| Gene Symbol and Synonyms | 2610306H15Rik,C10orf13,FGF-BP3,FGFBP3,RGD1560326 |
| Uniprot Accession | Q8TAT2 |
| Uniprot Entry Name | FGFP3_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000174721 |
| Target Classification | N/A |
The target: FGFBP3, gene name: FGFBP3, also named as C10orf13, FGF-BP3. Enables fibroblast growth factor binding activity and heparin binding activity. Acts upstream of or within positive regulation of fibroblast growth factor receptor signaling pathway and positive regulation of vascular permeability. Located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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