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Anti-FGF20/ FGF-20/ RHDA2 functional antibody
Anti-FGF20/ FGF-20/ RHDA2 functional antibody for cell culture, ELISA & in-vivo assay
Go to FGF20/FGF20 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0919-Ab-1/ GM-Tg-hg-SE0919-Ab-2 | Anti-Human FGF20 monoclonal antibody | Human |
| GM-Tg-rg-SE0919-Ab-1/ GM-Tg-rg-SE0919-Ab-2 | Anti-Rat FGF20 monoclonal antibody | Rat |
| GM-Tg-mg-SE0919-Ab-1/ GM-Tg-mg-SE0919-Ab-2 | Anti-Mouse FGF20 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0919-Ab-1/ GM-Tg-cynog-SE0919-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FGF20 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0919-Ab-1/ GM-Tg-felg-SE0919-Ab-2 | Anti-Feline FGF20 monoclonal antibody | Feline |
| GM-Tg-cang-SE0919-Ab-1/ GM-Tg-cang-SE0919-Ab-2 | Anti-Canine FGF20 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0919-Ab-1/ GM-Tg-bovg-SE0919-Ab-2 | Anti-Bovine FGF20 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0919-Ab-1/ GM-Tg-equg-SE0919-Ab-2 | Anti-Equine FGF20 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0919-Ab-1/ GM-Tg-hg-SE0919-Ab-2; GM-Tg-rg-SE0919-Ab-1/ GM-Tg-rg-SE0919-Ab-2; GM-Tg-mg-SE0919-Ab-1/ GM-Tg-mg-SE0919-Ab-2; GM-Tg-cynog-SE0919-Ab-1/ GM-Tg-cynog-SE0919-Ab-2; GM-Tg-felg-SE0919-Ab-1/ GM-Tg-felg-SE0919-Ab-2; GM-Tg-cang-SE0919-Ab-1/ GM-Tg-cang-SE0919-Ab-2; GM-Tg-bovg-SE0919-Ab-1/ GM-Tg-bovg-SE0919-Ab-2; GM-Tg-equg-SE0919-Ab-1/ GM-Tg-equg-SE0919-Ab-2 |
| Products Name | Anti-FGF20 monoclonal antibody |
| Format | mab |
| Target Name | FGF20 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FGF20 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0919-Ag-1 | Recombinant multi-species FGF20/ FGF-20/ RHDA2 protein |
| Cytokine | GM-Tg-g-SE0919-Ag-1 | fibroblast growth factor 20 (FGF20) protein |
| ORF Viral Vector | vGMLP001865 | human FGF20 Lentivirus particle |
| ORF Viral Vector | pGMLP001865 | human FGF20 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000696 | mouse Fgf20 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000696 | mouse Fgf20 Lentivirus particle |
Target information
| Target ID | GM-SE0919 |
| Target Name | FGF20 |
| Gene ID | 26281,80857,66017,701847,100855820,101083766,539083,100050037 |
| Gene Symbol and Synonyms | FGF-20,FGF20,Fgf4a,RHDA2 |
| Uniprot Accession | Q9NP95,Q9EST9 |
| Uniprot Entry Name | FGF20_HUMAN,FGF20_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000078579 |
| Target Classification | N/A |
The target: FGF20, gene name: FGF20, also named as FGF-20, RHDA2. The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility. [provided by RefSeq, Oct 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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