Anti-ERFE/ C1QTNF15/ CTRP15 functional antibody

Anti-ERFE/ C1QTNF15/ CTRP15 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ERFE/ERFE products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0908-Ab-1/ GM-Tg-hg-SE0908-Ab-2Anti-Human ERFE monoclonal antibodyHuman
GM-Tg-rg-SE0908-Ab-1/ GM-Tg-rg-SE0908-Ab-2Anti-Rat ERFE monoclonal antibodyRat
GM-Tg-mg-SE0908-Ab-1/ GM-Tg-mg-SE0908-Ab-2Anti-Mouse ERFE monoclonal antibodyMouse
GM-Tg-cynog-SE0908-Ab-1/ GM-Tg-cynog-SE0908-Ab-2Anti-Cynomolgus/ Rhesus macaque ERFE monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0908-Ab-1/ GM-Tg-felg-SE0908-Ab-2Anti-Feline ERFE monoclonal antibodyFeline
GM-Tg-cang-SE0908-Ab-1/ GM-Tg-cang-SE0908-Ab-2Anti-Canine ERFE monoclonal antibodyCanine
GM-Tg-bovg-SE0908-Ab-1/ GM-Tg-bovg-SE0908-Ab-2Anti-Bovine ERFE monoclonal antibodyBovine
GM-Tg-equg-SE0908-Ab-1/ GM-Tg-equg-SE0908-Ab-2Anti-Equine ERFE monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0908-Ab-1/ GM-Tg-hg-SE0908-Ab-2; GM-Tg-rg-SE0908-Ab-1/ GM-Tg-rg-SE0908-Ab-2;
GM-Tg-mg-SE0908-Ab-1/ GM-Tg-mg-SE0908-Ab-2; GM-Tg-cynog-SE0908-Ab-1/ GM-Tg-cynog-SE0908-Ab-2;
GM-Tg-felg-SE0908-Ab-1/ GM-Tg-felg-SE0908-Ab-2; GM-Tg-cang-SE0908-Ab-1/ GM-Tg-cang-SE0908-Ab-2;
GM-Tg-bovg-SE0908-Ab-1/ GM-Tg-bovg-SE0908-Ab-2; GM-Tg-equg-SE0908-Ab-1/ GM-Tg-equg-SE0908-Ab-2
Products NameAnti-ERFE monoclonal antibody
Formatmab
Target NameERFE
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ERFE benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    SDS-PAGE results of GM-Tg-hg-IO017-Ab-1
    HPLC results of GM-Tg-hg-SE0908-Ab-1-HPLC

    Figure. >95% purity by SDS-PAGE under reduced conditions, 98.863% purity by SEC-HPLC test.

    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0908-Ag-1Recombinant multi-species ERFE/ C1QTNF15/ CTRP15 protein


    Target information

    Target IDGM-SE0908
    Target NameERFE
    Gene ID151176,227358,681056,706226,102157118,105260877,101905782,102148534
    Gene Symbol and Synonyms4832406C22,C1QTNF15,CTRP15,ERFE,FAM132B,myonectin
    Uniprot AccessionQ4G0M1,D4AB34
    Uniprot Entry NameERFE_HUMAN,ERFE_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000178752
    Target ClassificationN/A

    The target: ERFE, gene name: ERFE, also named as C1QTNF15, CTRP15, FAM132B. Predicted to enable hormone activity. Predicted to be involved in several processes, including negative regulation of gluconeogenesis; positive regulation of glucose import; and positive regulation of insulin receptor signaling pathway. Predicted to act upstream of or within positive regulation of fatty acid transport and regulation of fatty acid metabolic process. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.