Anti-EPYC/ DSPG3/ PGLB functional antibody

Anti-EPYC/ DSPG3/ PGLB functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to EPYC/EPYC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0907-Ab-1/ GM-Tg-hg-SE0907-Ab-2Anti-Human EPYC monoclonal antibodyHuman
GM-Tg-rg-SE0907-Ab-1/ GM-Tg-rg-SE0907-Ab-2Anti-Rat EPYC monoclonal antibodyRat
GM-Tg-mg-SE0907-Ab-1/ GM-Tg-mg-SE0907-Ab-2Anti-Mouse EPYC monoclonal antibodyMouse
GM-Tg-cynog-SE0907-Ab-1/ GM-Tg-cynog-SE0907-Ab-2Anti-Cynomolgus/ Rhesus macaque EPYC monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0907-Ab-1/ GM-Tg-felg-SE0907-Ab-2Anti-Feline EPYC monoclonal antibodyFeline
GM-Tg-cang-SE0907-Ab-1/ GM-Tg-cang-SE0907-Ab-2Anti-Canine EPYC monoclonal antibodyCanine
GM-Tg-bovg-SE0907-Ab-1/ GM-Tg-bovg-SE0907-Ab-2Anti-Bovine EPYC monoclonal antibodyBovine
GM-Tg-equg-SE0907-Ab-1/ GM-Tg-equg-SE0907-Ab-2Anti-Equine EPYC monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0907-Ab-1/ GM-Tg-hg-SE0907-Ab-2; GM-Tg-rg-SE0907-Ab-1/ GM-Tg-rg-SE0907-Ab-2;
GM-Tg-mg-SE0907-Ab-1/ GM-Tg-mg-SE0907-Ab-2; GM-Tg-cynog-SE0907-Ab-1/ GM-Tg-cynog-SE0907-Ab-2;
GM-Tg-felg-SE0907-Ab-1/ GM-Tg-felg-SE0907-Ab-2; GM-Tg-cang-SE0907-Ab-1/ GM-Tg-cang-SE0907-Ab-2;
GM-Tg-bovg-SE0907-Ab-1/ GM-Tg-bovg-SE0907-Ab-2; GM-Tg-equg-SE0907-Ab-1/ GM-Tg-equg-SE0907-Ab-2
Products NameAnti-EPYC monoclonal antibody
Formatmab
Target NameEPYC
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-EPYC benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0907-Ag-1Recombinant multi-species EPYC/ DSPG3/ PGLB protein


    Target information

    Target IDGM-SE0907
    Target NameEPYC
    Gene ID1833,13516,314772,709645,100855602,101100490,281747,100051709
    Gene Symbol and SynonymsDSPG3,EPYC,Pg-Lb,PGLB,SLRR3B
    Uniprot AccessionQ99645,P79119
    Uniprot Entry NameEPYC_HUMAN,EPYC_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000083782
    Target ClassificationN/A

    The target: EPYC, gene name: EPYC, also named as DSPG3, PGLB, Pg-Lb, SLRR3B. Dermatan sulfate proteoglycan 3 is a member of the small leucine-rich repeat proteoglycan family. This gene is composed of seven exons. It regulates fibrillogenesis by interacting with collagen fibrils and other extracellular matrix proteins. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.