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Anti-CXCL5/ ENA-78/ SCYB5 functional antibody
Anti-CXCL5/ ENA-78/ SCYB5 functional antibody for cell culture, ELISA & in-vivo assay
Go to CXCL5/CXCL5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0844-Ab-1/ GM-Tg-hg-SE0844-Ab-2 | Anti-Human CXCL5 monoclonal antibody | Human |
| GM-Tg-rg-SE0844-Ab-1/ GM-Tg-rg-SE0844-Ab-2 | Anti-Rat CXCL5 monoclonal antibody | Rat |
| GM-Tg-mg-SE0844-Ab-1/ GM-Tg-mg-SE0844-Ab-2 | Anti-Mouse CXCL5 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0844-Ab-1/ GM-Tg-cynog-SE0844-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CXCL5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0844-Ab-1/ GM-Tg-felg-SE0844-Ab-2 | Anti-Feline CXCL5 monoclonal antibody | Feline |
| GM-Tg-cang-SE0844-Ab-1/ GM-Tg-cang-SE0844-Ab-2 | Anti-Canine CXCL5 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0844-Ab-1/ GM-Tg-bovg-SE0844-Ab-2 | Anti-Bovine CXCL5 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0844-Ab-1/ GM-Tg-equg-SE0844-Ab-2 | Anti-Equine CXCL5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0844-Ab-1/ GM-Tg-hg-SE0844-Ab-2; GM-Tg-rg-SE0844-Ab-1/ GM-Tg-rg-SE0844-Ab-2; GM-Tg-mg-SE0844-Ab-1/ GM-Tg-mg-SE0844-Ab-2; GM-Tg-cynog-SE0844-Ab-1/ GM-Tg-cynog-SE0844-Ab-2; GM-Tg-felg-SE0844-Ab-1/ GM-Tg-felg-SE0844-Ab-2; GM-Tg-cang-SE0844-Ab-1/ GM-Tg-cang-SE0844-Ab-2; GM-Tg-bovg-SE0844-Ab-1/ GM-Tg-bovg-SE0844-Ab-2; GM-Tg-equg-SE0844-Ab-1/ GM-Tg-equg-SE0844-Ab-2 |
| Products Name | Anti-CXCL5 monoclonal antibody |
| Format | mab |
| Target Name | CXCL5 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CXCL5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0844-Ag-1 | Recombinant multi-species CXCL5/ ENA-78/ SCYB5 protein |
| Cytokine | GM-Tg-g-SE0844-Ag-1 | chemokine (C-X-C motif) ligand 15 (CXCL15) protein |
| ORF Viral Vector | vGMLP002668 | human CXCL5 Lentivirus particle |
| ORF Viral Vector | pGMLP002668 | human CXCL5 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000562 | mouse Cxcl5 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000562 | mouse Cxcl5 Lentivirus particle |
Target information
| Target ID | GM-SE0844 |
| Target Name | CXCL5 |
| Gene ID | 6374 |
| Gene Symbol and Synonyms | CXCL5,ENA-78,SCYB5 |
| Uniprot Accession | P42830 |
| Uniprot Entry Name | CXCL5_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Cytokine Target |
| Disease | Prostate Cancer, Malignant neoplasm of bladder |
| Gene Ensembl | ENSG00000163735 |
| Target Classification | N/A |
The target: CXCL5, gene name: CXCL5, also named as ENA-78, SCYB5. This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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