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Anti-CASB/ CSN2 functional antibody
Anti-CASB/ CSN2 functional antibody for cell culture, ELISA & in-vivo assay
Go to CSN2/CSN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0830-Ab-1/ GM-Tg-hg-SE0830-Ab-2 | Anti-Human CSN2 monoclonal antibody | Human |
| GM-Tg-rg-SE0830-Ab-1/ GM-Tg-rg-SE0830-Ab-2 | Anti-Rat CSN2 monoclonal antibody | Rat |
| GM-Tg-mg-SE0830-Ab-1/ GM-Tg-mg-SE0830-Ab-2 | Anti-Mouse CSN2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0830-Ab-1/ GM-Tg-cynog-SE0830-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CSN2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0830-Ab-1/ GM-Tg-felg-SE0830-Ab-2 | Anti-Feline CSN2 monoclonal antibody | Feline |
| GM-Tg-cang-SE0830-Ab-1/ GM-Tg-cang-SE0830-Ab-2 | Anti-Canine CSN2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0830-Ab-1/ GM-Tg-bovg-SE0830-Ab-2 | Anti-Bovine CSN2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0830-Ab-1/ GM-Tg-equg-SE0830-Ab-2 | Anti-Equine CSN2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0830-Ab-1/ GM-Tg-hg-SE0830-Ab-2; GM-Tg-rg-SE0830-Ab-1/ GM-Tg-rg-SE0830-Ab-2; GM-Tg-mg-SE0830-Ab-1/ GM-Tg-mg-SE0830-Ab-2; GM-Tg-cynog-SE0830-Ab-1/ GM-Tg-cynog-SE0830-Ab-2; GM-Tg-felg-SE0830-Ab-1/ GM-Tg-felg-SE0830-Ab-2; GM-Tg-cang-SE0830-Ab-1/ GM-Tg-cang-SE0830-Ab-2; GM-Tg-bovg-SE0830-Ab-1/ GM-Tg-bovg-SE0830-Ab-2; GM-Tg-equg-SE0830-Ab-1/ GM-Tg-equg-SE0830-Ab-2 |
| Products Name | Anti-CSN2 monoclonal antibody |
| Format | mab |
| Target Name | CSN2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CSN2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0830-Ag-1 | Recombinant multi-species CASB/ CSN2 protein |
| ORF Viral Vector | vGMLP002067 | human CSN2 Lentivirus particle |
| ORF Viral Vector | pGMLP002067 | human CSN2 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000358 | mouse Csn2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000358 | mouse Csn2 Lentivirus particle |
Target information
| Target ID | GM-SE0830 |
| Target Name | CSN2 |
| Gene ID | 1447,12991,29173,707520,403644,101098299,281099,100033903 |
| Gene Symbol and Synonyms | CASB,CSN2,Csnb,PDC213 |
| Uniprot Accession | P05814,P02665,P02666,Q9GKK3 |
| Uniprot Entry Name | CASB_HUMAN,CASB_RAT,CASB_BOVIN,CASB_HORSE |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000135222 |
| Target Classification | N/A |
The target: CSN2, gene name: CSN2, also named as CASB. This gene is a member of the beta casein family. There are two types of casein protein, beta (encoded by this gene) and kappa, both of which are secreted in human milk. Beta casein is the principal protein in human milk and the primary source of essential amino acids for a suckling infant. Beta and kappa casein proteins acting together form spherical micelles which bind within them important dietary minerals, such as calcium and phosphorous. In addition, the C-terminal 14 aa of the protein has antimicrobial activity, especially in preterm milk, displaying antibacterial activity against S. aureus and Y. enterocolitica. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2020].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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