- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-COL11/ COLEC11/ 3MC2 functional antibody
Anti-COL11/ COLEC11/ 3MC2 functional antibody for cell culture, ELISA & in-vivo assay
Go to COLEC11/COLEC11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0808-Ab-1/ GM-Tg-hg-SE0808-Ab-2 | Anti-Human COLEC11 monoclonal antibody | Human |
| GM-Tg-rg-SE0808-Ab-1/ GM-Tg-rg-SE0808-Ab-2 | Anti-Rat COLEC11 monoclonal antibody | Rat |
| GM-Tg-mg-SE0808-Ab-1/ GM-Tg-mg-SE0808-Ab-2 | Anti-Mouse COLEC11 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0808-Ab-1/ GM-Tg-cynog-SE0808-Ab-2 | Anti-Cynomolgus/ Rhesus macaque COLEC11 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0808-Ab-1/ GM-Tg-felg-SE0808-Ab-2 | Anti-Feline COLEC11 monoclonal antibody | Feline |
| GM-Tg-cang-SE0808-Ab-1/ GM-Tg-cang-SE0808-Ab-2 | Anti-Canine COLEC11 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0808-Ab-1/ GM-Tg-bovg-SE0808-Ab-2 | Anti-Bovine COLEC11 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0808-Ab-1/ GM-Tg-equg-SE0808-Ab-2 | Anti-Equine COLEC11 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0808-Ab-1/ GM-Tg-hg-SE0808-Ab-2; GM-Tg-rg-SE0808-Ab-1/ GM-Tg-rg-SE0808-Ab-2; GM-Tg-mg-SE0808-Ab-1/ GM-Tg-mg-SE0808-Ab-2; GM-Tg-cynog-SE0808-Ab-1/ GM-Tg-cynog-SE0808-Ab-2; GM-Tg-felg-SE0808-Ab-1/ GM-Tg-felg-SE0808-Ab-2; GM-Tg-cang-SE0808-Ab-1/ GM-Tg-cang-SE0808-Ab-2; GM-Tg-bovg-SE0808-Ab-1/ GM-Tg-bovg-SE0808-Ab-2; GM-Tg-equg-SE0808-Ab-1/ GM-Tg-equg-SE0808-Ab-2 |
| Products Name | Anti-COLEC11 monoclonal antibody |
| Format | mab |
| Target Name | COLEC11 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-COLEC11 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0808-Ag-1 | Recombinant multi-species COL11/ COLEC11/ 3MC2 protein |
| ORF Viral Vector | pGMLP004916 | human COLEC11 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004916 | human COLEC11 Lentivirus particle |
Target information
| Target ID | GM-SE0808 |
| Target Name | COLEC11 |
| Gene ID | 78989,71693,366588,707223,482958,101091014,613991,100072828 |
| Gene Symbol and Synonyms | 3MC2,CL-11,CL-K1,CL-K1-I,CL-K1-II,CL-K1-IIa,CL-K1-IIb,CLK1,COLEC11 |
| Uniprot Accession | Q9BWP8,Q17QH6 |
| Uniprot Entry Name | COL11_HUMAN,COL11_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000118004 |
| Target Classification | N/A |
The target: COLEC11, gene name: COLEC11, also named as 3MC2, CL-K1-I, CL-K1-II, CL-K1-IIa, CL-K1-IIb, CLK1. This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. The encoded protein binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC syndrome-2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
