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Anti-CCL14/ CC-1/ CC-3 functional antibody
Anti-CCL14/ CC-1/ CC-3 functional antibody for cell culture, ELISA & in-vivo assay
Go to CCL14/CCL14 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0740-Ab-1/ GM-Tg-hg-SE0740-Ab-2 | Anti-Human CCL14 monoclonal antibody | Human |
| GM-Tg-rg-SE0740-Ab-1/ GM-Tg-rg-SE0740-Ab-2 | Anti-Rat CCL14 monoclonal antibody | Rat |
| GM-Tg-mg-SE0740-Ab-1/ GM-Tg-mg-SE0740-Ab-2 | Anti-Mouse CCL14 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0740-Ab-1/ GM-Tg-cynog-SE0740-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CCL14 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0740-Ab-1/ GM-Tg-felg-SE0740-Ab-2 | Anti-Feline CCL14 monoclonal antibody | Feline |
| GM-Tg-cang-SE0740-Ab-1/ GM-Tg-cang-SE0740-Ab-2 | Anti-Canine CCL14 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0740-Ab-1/ GM-Tg-bovg-SE0740-Ab-2 | Anti-Bovine CCL14 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0740-Ab-1/ GM-Tg-equg-SE0740-Ab-2 | Anti-Equine CCL14 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0740-Ab-1/ GM-Tg-hg-SE0740-Ab-2; GM-Tg-rg-SE0740-Ab-1/ GM-Tg-rg-SE0740-Ab-2; GM-Tg-mg-SE0740-Ab-1/ GM-Tg-mg-SE0740-Ab-2; GM-Tg-cynog-SE0740-Ab-1/ GM-Tg-cynog-SE0740-Ab-2; GM-Tg-felg-SE0740-Ab-1/ GM-Tg-felg-SE0740-Ab-2; GM-Tg-cang-SE0740-Ab-1/ GM-Tg-cang-SE0740-Ab-2; GM-Tg-bovg-SE0740-Ab-1/ GM-Tg-bovg-SE0740-Ab-2; GM-Tg-equg-SE0740-Ab-1/ GM-Tg-equg-SE0740-Ab-2 |
| Products Name | Anti-CCL14 monoclonal antibody |
| Format | mab |
| Target Name | CCL14 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CCL14 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0740-Ag-1 | Recombinant multi-species CCL14/ CC-1/ CC-3 protein |
| Cytokine | GM-Tg-g-SE0740-Ag-1 | chemokine (C-C motif) ligand 14 (CCL14) protein |
Target information
| Target ID | GM-SE0740 |
| Target Name | CCL14 |
| Gene ID | 6358,716765 |
| Gene Symbol and Synonyms | CC-1,CC-3,CCL14,CKB1,HCC-1,HCC-1(1-74),HCC-1/HCC-3,HCC-3,MCIF,NCC-2,NCC2,SCYA14,SCYL2,SY14 |
| Uniprot Accession | Q16627 |
| Uniprot Entry Name | CCL14_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000276409 |
| Target Classification | N/A |
The target: CCL14, gene name: CCL14, also named as CC-1, CC-3, CKB1, HCC-1, HCC-1(1-74), HCC-1/HCC-3, HCC-3, MCIF, NCC-2, NCC2, SCYA14, SCYL2, SY14. This gene, chemokine (C-C motif) ligand 14, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene induces changes in intracellular calcium concentration and enzyme release in monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Read-through transcripts are also expressed that include exons from the upstream cytokine gene, chemokine (C-C motif) ligand 15, and are represented as GeneID: 348249. [provided by RefSeq, Dec 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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