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Anti-BRNP3/ BRINP3/ DBCCR1L functional antibody
Anti-BRNP3/ BRINP3/ DBCCR1L functional antibody for cell culture, ELISA & in-vivo assay
Go to BRINP3/BRINP3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0697-Ab-1/ GM-Tg-hg-SE0697-Ab-2 | Anti-Human BRINP3 monoclonal antibody | Human |
| GM-Tg-rg-SE0697-Ab-1/ GM-Tg-rg-SE0697-Ab-2 | Anti-Rat BRINP3 monoclonal antibody | Rat |
| GM-Tg-mg-SE0697-Ab-1/ GM-Tg-mg-SE0697-Ab-2 | Anti-Mouse BRINP3 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0697-Ab-1/ GM-Tg-cynog-SE0697-Ab-2 | Anti-Cynomolgus/ Rhesus macaque BRINP3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0697-Ab-1/ GM-Tg-felg-SE0697-Ab-2 | Anti-Feline BRINP3 monoclonal antibody | Feline |
| GM-Tg-cang-SE0697-Ab-1/ GM-Tg-cang-SE0697-Ab-2 | Anti-Canine BRINP3 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0697-Ab-1/ GM-Tg-bovg-SE0697-Ab-2 | Anti-Bovine BRINP3 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0697-Ab-1/ GM-Tg-equg-SE0697-Ab-2 | Anti-Equine BRINP3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0697-Ab-1/ GM-Tg-hg-SE0697-Ab-2; GM-Tg-rg-SE0697-Ab-1/ GM-Tg-rg-SE0697-Ab-2; GM-Tg-mg-SE0697-Ab-1/ GM-Tg-mg-SE0697-Ab-2; GM-Tg-cynog-SE0697-Ab-1/ GM-Tg-cynog-SE0697-Ab-2; GM-Tg-felg-SE0697-Ab-1/ GM-Tg-felg-SE0697-Ab-2; GM-Tg-cang-SE0697-Ab-1/ GM-Tg-cang-SE0697-Ab-2; GM-Tg-bovg-SE0697-Ab-1/ GM-Tg-bovg-SE0697-Ab-2; GM-Tg-equg-SE0697-Ab-1/ GM-Tg-equg-SE0697-Ab-2 |
| Products Name | Anti-BRINP3 monoclonal antibody |
| Format | mab |
| Target Name | BRINP3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-BRINP3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0697-Ag-1 | Recombinant multi-species BRNP3/ BRINP3/ DBCCR1L protein |
| ORF Viral Vector | pGMLP001169 | human BRINP3 Lentivirus plasmid |
| ORF Viral Vector | vGMLP001169 | human BRINP3 Lentivirus particle |
| ORF Viral Vector | pGMLPm003627 | mouse Brinp3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003627 | mouse Brinp3 Lentivirus particle |
Target information
| Target ID | GM-SE0697 |
| Target Name | BRINP3 |
| Gene ID | 339479,215378,286901,713093,478959,101089978,531710,100050767 |
| Gene Symbol and Synonyms | B830045N13Rik,BRINP3,DBCCR1L,DBCCR1L1,FAM5C |
| Uniprot Accession | Q76B58,Q8K1M7 |
| Uniprot Entry Name | BRNP3_HUMAN,BRNP3_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000162670 |
| Target Classification | N/A |
The target: BRINP3, gene name: BRINP3, also named as DBCCR1L, DBCCR1L1, FAM5C. This gene is overexpressed in pituitary tumors but is underexpressed in tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and an association of this gene with myocardial infarction has been demonstrated. Finally, hypermethylation of this gene may find usefulness as a biomarker for gastric cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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