Anti-AGGF1/ GPATC7/ GPATCH7 functional antibody

Anti-AGGF1/ GPATC7/ GPATCH7 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to AGGF1/AGGF1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0656-Ab-1/ GM-Tg-hg-SE0656-Ab-2Anti-Human AGGF1 monoclonal antibodyHuman
GM-Tg-rg-SE0656-Ab-1/ GM-Tg-rg-SE0656-Ab-2Anti-Rat AGGF1 monoclonal antibodyRat
GM-Tg-mg-SE0656-Ab-1/ GM-Tg-mg-SE0656-Ab-2Anti-Mouse AGGF1 monoclonal antibodyMouse
GM-Tg-cynog-SE0656-Ab-1/ GM-Tg-cynog-SE0656-Ab-2Anti-Cynomolgus/ Rhesus macaque AGGF1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0656-Ab-1/ GM-Tg-felg-SE0656-Ab-2Anti-Feline AGGF1 monoclonal antibodyFeline
GM-Tg-cang-SE0656-Ab-1/ GM-Tg-cang-SE0656-Ab-2Anti-Canine AGGF1 monoclonal antibodyCanine
GM-Tg-bovg-SE0656-Ab-1/ GM-Tg-bovg-SE0656-Ab-2Anti-Bovine AGGF1 monoclonal antibodyBovine
GM-Tg-equg-SE0656-Ab-1/ GM-Tg-equg-SE0656-Ab-2Anti-Equine AGGF1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0656-Ab-1/ GM-Tg-hg-SE0656-Ab-2; GM-Tg-rg-SE0656-Ab-1/ GM-Tg-rg-SE0656-Ab-2;
GM-Tg-mg-SE0656-Ab-1/ GM-Tg-mg-SE0656-Ab-2; GM-Tg-cynog-SE0656-Ab-1/ GM-Tg-cynog-SE0656-Ab-2;
GM-Tg-felg-SE0656-Ab-1/ GM-Tg-felg-SE0656-Ab-2; GM-Tg-cang-SE0656-Ab-1/ GM-Tg-cang-SE0656-Ab-2;
GM-Tg-bovg-SE0656-Ab-1/ GM-Tg-bovg-SE0656-Ab-2; GM-Tg-equg-SE0656-Ab-1/ GM-Tg-equg-SE0656-Ab-2
Products NameAnti-AGGF1 monoclonal antibody
Formatmab
Target NameAGGF1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-AGGF1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0656-Ag-1Recombinant multi-species AGGF1/ GPATC7/ GPATCH7 protein


    Target information

    Target IDGM-SE0656
    Target NameAGGF1
    Gene ID55109,66549,310005,707686,479176,101083397,511650,100073274
    Gene Symbol and Synonyms2010009L17Rik,2310029P06Rik,AGGF1,GPATC7,GPATCH7,HSU84971,HUS84971,Peg3,RGD1310888,VG5Q
    Uniprot AccessionQ8N302
    Uniprot Entry NameAGGF1_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000164252
    Target ClassificationN/A

    The target: AGGF1, gene name: AGGF1, also named as GPATC7, GPATCH7, HSU84971, HUS84971, VG5Q. This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.[provided by RefSeq, Sep 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.