Anti-IGFL2/ UNQ645/ VPRI645 functional antibody

Anti-IGFL2/ UNQ645/ VPRI645 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to IGFL2/IGFL2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0589-Ab-1/ GM-Tg-hg-SE0589-Ab-2Anti-Human IGFL2 monoclonal antibodyHuman
GM-Tg-rg-SE0589-Ab-1/ GM-Tg-rg-SE0589-Ab-2Anti-Rat IGFL2 monoclonal antibodyRat
GM-Tg-mg-SE0589-Ab-1/ GM-Tg-mg-SE0589-Ab-2Anti-Mouse IGFL2 monoclonal antibodyMouse
GM-Tg-cynog-SE0589-Ab-1/ GM-Tg-cynog-SE0589-Ab-2Anti-Cynomolgus/ Rhesus macaque IGFL2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0589-Ab-1/ GM-Tg-felg-SE0589-Ab-2Anti-Feline IGFL2 monoclonal antibodyFeline
GM-Tg-cang-SE0589-Ab-1/ GM-Tg-cang-SE0589-Ab-2Anti-Canine IGFL2 monoclonal antibodyCanine
GM-Tg-bovg-SE0589-Ab-1/ GM-Tg-bovg-SE0589-Ab-2Anti-Bovine IGFL2 monoclonal antibodyBovine
GM-Tg-equg-SE0589-Ab-1/ GM-Tg-equg-SE0589-Ab-2Anti-Equine IGFL2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0589-Ab-1/ GM-Tg-hg-SE0589-Ab-2; GM-Tg-rg-SE0589-Ab-1/ GM-Tg-rg-SE0589-Ab-2;
GM-Tg-mg-SE0589-Ab-1/ GM-Tg-mg-SE0589-Ab-2; GM-Tg-cynog-SE0589-Ab-1/ GM-Tg-cynog-SE0589-Ab-2;
GM-Tg-felg-SE0589-Ab-1/ GM-Tg-felg-SE0589-Ab-2; GM-Tg-cang-SE0589-Ab-1/ GM-Tg-cang-SE0589-Ab-2;
GM-Tg-bovg-SE0589-Ab-1/ GM-Tg-bovg-SE0589-Ab-2; GM-Tg-equg-SE0589-Ab-1/ GM-Tg-equg-SE0589-Ab-2
Products NameAnti-IGFL2 monoclonal antibody
Formatmab
Target NameIGFL2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IGFL2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0589-Ag-1Recombinant multi-species IGFL2/ UNQ645/ VPRI645 protein
    CytokineGM-Tg-g-SE0589-Ag-1IGF-like family member 2 (IGFL2) protein


    Target information

    Target IDGM-SE0589
    Target NameIGFL2
    Gene ID147920
    Gene Symbol and SynonymsIGFL2,UNQ645,VPRI645
    Uniprot AccessionQ6UWQ7
    Uniprot Entry NameIGFL2_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryCytokine Target
    DiseaseN/A
    Gene EnsemblENSG00000204866
    Target ClassificationN/A

    The target: IGFL2, gene name: IGFL2, also named as UNQ645, VPRI645. IGFL2 belongs to the insulin-like growth factor (IGF; see MIM 147440) family of signaling molecules that play critical roles in cellular energy metabolism and in growth and development, especially prenatal growth (Emtage et al., 2006 [PubMed 16890402]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.