Anti-WNT2B/ WNT13 functional antibody
Anti-WNT2B/ WNT13 functional antibody for cell culture, ELISA & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE0558-Ab-1/ GM-Tg-hg-SE0558-Ab-2 | Anti-Human WNT2B monoclonal antibody | Human |
GM-Tg-rg-SE0558-Ab-1/ GM-Tg-rg-SE0558-Ab-2 | Anti-Rat WNT2B monoclonal antibody | Rat |
GM-Tg-mg-SE0558-Ab-1/ GM-Tg-mg-SE0558-Ab-2 | Anti-Mouse WNT2B monoclonal antibody | Mouse |
GM-Tg-cynog-SE0558-Ab-1/ GM-Tg-cynog-SE0558-Ab-2 | Anti-Cynomolgus/ Rhesus macaque WNT2B monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE0558-Ab-1/ GM-Tg-felg-SE0558-Ab-2 | Anti-Feline WNT2B monoclonal antibody | Feline |
GM-Tg-cang-SE0558-Ab-1/ GM-Tg-cang-SE0558-Ab-2 | Anti-Canine WNT2B monoclonal antibody | Canine |
GM-Tg-bovg-SE0558-Ab-1/ GM-Tg-bovg-SE0558-Ab-2 | Anti-Bovine WNT2B monoclonal antibody | Bovine |
GM-Tg-equg-SE0558-Ab-1/ GM-Tg-equg-SE0558-Ab-2 | Anti-Equine WNT2B monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-SE0558-Ab-1/ GM-Tg-hg-SE0558-Ab-2; GM-Tg-rg-SE0558-Ab-1/ GM-Tg-rg-SE0558-Ab-2; GM-Tg-mg-SE0558-Ab-1/ GM-Tg-mg-SE0558-Ab-2; GM-Tg-cynog-SE0558-Ab-1/ GM-Tg-cynog-SE0558-Ab-2; GM-Tg-felg-SE0558-Ab-1/ GM-Tg-felg-SE0558-Ab-2; GM-Tg-cang-SE0558-Ab-1/ GM-Tg-cang-SE0558-Ab-2; GM-Tg-bovg-SE0558-Ab-1/ GM-Tg-bovg-SE0558-Ab-2; GM-Tg-equg-SE0558-Ab-1/ GM-Tg-equg-SE0558-Ab-2 |
Products Name | Anti-WNT2B monoclonal antibody |
Format | mab |
Target Name | WNT2B |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-WNT2B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-SE0558-Ag-1 | Recombinant multi-species WNT2B/ WNT13 protein |
Cytokine | GM-Tg-g-SE0558-Ag-1 | wingless-type MMTV integration site family, member 2B (WNT2B) protein |
ORF Viral Vector | pGMLPm005136 | mouse Wnt2b Lentivirus plasmid |
ORF Viral Vector | vGMLPm005136 | mouse Wnt2b Lentivirus particle |
Target information
Target ID | GM-SE0558 |
Target Name | WNT2B |
Gene ID | 7482,22414,116466,705773,483220,101080904,445420,100063931 |
Gene Symbol and Synonyms | WNT13,WNT2B |
Uniprot Accession | Q93097 |
Uniprot Entry Name | WNT2B_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Cytokine Target |
Disease | N/A |
Gene Ensembl | ENSG00000134245 |
Target Classification | N/A |
The target: WNT2B, gene name: WNT2B, also named as WNT13. This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.