Anti-WNT2B/ WNT13 functional antibody

Anti-WNT2B/ WNT13 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to WNT2B/WNT2B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0558-Ab-1/ GM-Tg-hg-SE0558-Ab-2Anti-Human WNT2B monoclonal antibodyHuman
GM-Tg-rg-SE0558-Ab-1/ GM-Tg-rg-SE0558-Ab-2Anti-Rat WNT2B monoclonal antibodyRat
GM-Tg-mg-SE0558-Ab-1/ GM-Tg-mg-SE0558-Ab-2Anti-Mouse WNT2B monoclonal antibodyMouse
GM-Tg-cynog-SE0558-Ab-1/ GM-Tg-cynog-SE0558-Ab-2Anti-Cynomolgus/ Rhesus macaque WNT2B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0558-Ab-1/ GM-Tg-felg-SE0558-Ab-2Anti-Feline WNT2B monoclonal antibodyFeline
GM-Tg-cang-SE0558-Ab-1/ GM-Tg-cang-SE0558-Ab-2Anti-Canine WNT2B monoclonal antibodyCanine
GM-Tg-bovg-SE0558-Ab-1/ GM-Tg-bovg-SE0558-Ab-2Anti-Bovine WNT2B monoclonal antibodyBovine
GM-Tg-equg-SE0558-Ab-1/ GM-Tg-equg-SE0558-Ab-2Anti-Equine WNT2B monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0558-Ab-1/ GM-Tg-hg-SE0558-Ab-2; GM-Tg-rg-SE0558-Ab-1/ GM-Tg-rg-SE0558-Ab-2;
GM-Tg-mg-SE0558-Ab-1/ GM-Tg-mg-SE0558-Ab-2; GM-Tg-cynog-SE0558-Ab-1/ GM-Tg-cynog-SE0558-Ab-2;
GM-Tg-felg-SE0558-Ab-1/ GM-Tg-felg-SE0558-Ab-2; GM-Tg-cang-SE0558-Ab-1/ GM-Tg-cang-SE0558-Ab-2;
GM-Tg-bovg-SE0558-Ab-1/ GM-Tg-bovg-SE0558-Ab-2; GM-Tg-equg-SE0558-Ab-1/ GM-Tg-equg-SE0558-Ab-2
Products NameAnti-WNT2B monoclonal antibody
Formatmab
Target NameWNT2B
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-WNT2B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0558-Ag-1Recombinant multi-species WNT2B/ WNT13 protein
    CytokineGM-Tg-g-SE0558-Ag-1wingless-type MMTV integration site family, member 2B (WNT2B) protein
    ORF Viral VectorpGMLPm005136mouse Wnt2b Lentivirus plasmid
    ORF Viral VectorvGMLPm005136mouse Wnt2b Lentivirus particle


    Target information

    Target IDGM-SE0558
    Target NameWNT2B
    Gene ID7482,22414,116466,705773,483220,101080904,445420,100063931
    Gene Symbol and SynonymsWNT13,WNT2B
    Uniprot AccessionQ93097
    Uniprot Entry NameWNT2B_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryCytokine Target
    DiseaseN/A
    Gene EnsemblENSG00000134245
    Target ClassificationN/A

    The target: WNT2B, gene name: WNT2B, also named as WNT13. This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.