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Anti-MGT4A/ MGAT4A/ GNT-IV functional antibody
Anti-MGT4A/ MGAT4A/ GNT-IV functional antibody for cell culture, ELISA & in-vivo assay
Go to MGAT4A/MGAT4A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0345-Ab-1/ GM-Tg-hg-SE0345-Ab-2 | Anti-Human MGAT4A monoclonal antibody | Human |
| GM-Tg-rg-SE0345-Ab-1/ GM-Tg-rg-SE0345-Ab-2 | Anti-Rat MGAT4A monoclonal antibody | Rat |
| GM-Tg-mg-SE0345-Ab-1/ GM-Tg-mg-SE0345-Ab-2 | Anti-Mouse MGAT4A monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0345-Ab-1/ GM-Tg-cynog-SE0345-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MGAT4A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0345-Ab-1/ GM-Tg-felg-SE0345-Ab-2 | Anti-Feline MGAT4A monoclonal antibody | Feline |
| GM-Tg-cang-SE0345-Ab-1/ GM-Tg-cang-SE0345-Ab-2 | Anti-Canine MGAT4A monoclonal antibody | Canine |
| GM-Tg-bovg-SE0345-Ab-1/ GM-Tg-bovg-SE0345-Ab-2 | Anti-Bovine MGAT4A monoclonal antibody | Bovine |
| GM-Tg-equg-SE0345-Ab-1/ GM-Tg-equg-SE0345-Ab-2 | Anti-Equine MGAT4A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0345-Ab-1/ GM-Tg-hg-SE0345-Ab-2; GM-Tg-rg-SE0345-Ab-1/ GM-Tg-rg-SE0345-Ab-2; GM-Tg-mg-SE0345-Ab-1/ GM-Tg-mg-SE0345-Ab-2; GM-Tg-cynog-SE0345-Ab-1/ GM-Tg-cynog-SE0345-Ab-2; GM-Tg-felg-SE0345-Ab-1/ GM-Tg-felg-SE0345-Ab-2; GM-Tg-cang-SE0345-Ab-1/ GM-Tg-cang-SE0345-Ab-2; GM-Tg-bovg-SE0345-Ab-1/ GM-Tg-bovg-SE0345-Ab-2; GM-Tg-equg-SE0345-Ab-1/ GM-Tg-equg-SE0345-Ab-2 |
| Products Name | Anti-MGAT4A monoclonal antibody |
| Format | mab |
| Target Name | MGAT4A |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MGAT4A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0345-Ag-1 | Recombinant multi-species MGT4A/ MGAT4A/ GNT-IV protein |
Target information
| Target ID | GM-SE0345 |
| Target Name | MGAT4A |
| Gene ID | 11320,269181,367252,708094,474562,101088153,282276,100050964 |
| Gene Symbol and Synonyms | 9530018I07Rik,glcNAc-T-IVa,GnT-4a,GNT-IV,GNT-IVA,MGAT4A |
| Uniprot Accession | Q9UM21,Q5M854,O77836 |
| Uniprot Entry Name | MGT4A_HUMAN,MGT4A_RAT,MGT4A_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000071073 |
| Target Classification | N/A |
The target: MGAT4A, gene name: MGAT4A, also named as GNT-IV, GNT-IVA, GnT-4a. This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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