Anti-IFNE/ IFN-E1/ IFNT1 functional antibody

Anti-IFNE/ IFN-E1/ IFNT1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to IFNE/IFNE products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0277-Ab-1/ GM-Tg-hg-SE0277-Ab-2Anti-Human IFNE monoclonal antibodyHuman
GM-Tg-rg-SE0277-Ab-1/ GM-Tg-rg-SE0277-Ab-2Anti-Rat IFNE monoclonal antibodyRat
GM-Tg-mg-SE0277-Ab-1/ GM-Tg-mg-SE0277-Ab-2Anti-Mouse IFNE monoclonal antibodyMouse
GM-Tg-cynog-SE0277-Ab-1/ GM-Tg-cynog-SE0277-Ab-2Anti-Cynomolgus/ Rhesus macaque IFNE monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0277-Ab-1/ GM-Tg-felg-SE0277-Ab-2Anti-Feline IFNE monoclonal antibodyFeline
GM-Tg-cang-SE0277-Ab-1/ GM-Tg-cang-SE0277-Ab-2Anti-Canine IFNE monoclonal antibodyCanine
GM-Tg-bovg-SE0277-Ab-1/ GM-Tg-bovg-SE0277-Ab-2Anti-Bovine IFNE monoclonal antibodyBovine
GM-Tg-equg-SE0277-Ab-1/ GM-Tg-equg-SE0277-Ab-2Anti-Equine IFNE monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0277-Ab-1/ GM-Tg-hg-SE0277-Ab-2; GM-Tg-rg-SE0277-Ab-1/ GM-Tg-rg-SE0277-Ab-2;
GM-Tg-mg-SE0277-Ab-1/ GM-Tg-mg-SE0277-Ab-2; GM-Tg-cynog-SE0277-Ab-1/ GM-Tg-cynog-SE0277-Ab-2;
GM-Tg-felg-SE0277-Ab-1/ GM-Tg-felg-SE0277-Ab-2; GM-Tg-cang-SE0277-Ab-1/ GM-Tg-cang-SE0277-Ab-2;
GM-Tg-bovg-SE0277-Ab-1/ GM-Tg-bovg-SE0277-Ab-2; GM-Tg-equg-SE0277-Ab-1/ GM-Tg-equg-SE0277-Ab-2
Products NameAnti-IFNE monoclonal antibody
Formatmab
Target NameIFNE
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IFNE benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0277-Ag-1Recombinant multi-species IFNE/ IFN-E1/ IFNT1 protein
    CytokineGM-Tg-g-SE0277-Ag-1interferon, epsilon (IFNE) protein


    Target information

    Target IDGM-SE0277
    Target NameIFNE
    Gene ID338376,230405,108350996,106993736,111089992,101086758,101904725,100065067
    Gene Symbol and SynonymsIf1ea,IFN-E,Ifn-tau-1,IFNE,IFNE1,IFNT1,INFE1,PRO655,RGD1565065
    Uniprot AccessionQ86WN2
    Uniprot Entry NameIFNE_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryCytokine Target
    DiseaseN/A
    Gene EnsemblENSG00000184995
    Target ClassificationN/A

    The target: IFNE, gene name: IFNE, also named as IFN-E1, IFNT1, INFE1, PRO655, IFNE. Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including B cell activation; defense response to other organism; and lymphocyte activation involved in immune response. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.