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Anti-FCRLA/ FCRL/ FCRL1 functional antibody
Anti-FCRLA/ FCRL/ FCRL1 functional antibody for cell culture, ELISA & in-vivo assay
Go to FCRLA/FCRLA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0213-Ab-1/ GM-Tg-hg-SE0213-Ab-2 | Anti-Human FCRLA monoclonal antibody | Human |
| GM-Tg-rg-SE0213-Ab-1/ GM-Tg-rg-SE0213-Ab-2 | Anti-Rat FCRLA monoclonal antibody | Rat |
| GM-Tg-mg-SE0213-Ab-1/ GM-Tg-mg-SE0213-Ab-2 | Anti-Mouse FCRLA monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0213-Ab-1/ GM-Tg-cynog-SE0213-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FCRLA monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0213-Ab-1/ GM-Tg-felg-SE0213-Ab-2 | Anti-Feline FCRLA monoclonal antibody | Feline |
| GM-Tg-cang-SE0213-Ab-1/ GM-Tg-cang-SE0213-Ab-2 | Anti-Canine FCRLA monoclonal antibody | Canine |
| GM-Tg-bovg-SE0213-Ab-1/ GM-Tg-bovg-SE0213-Ab-2 | Anti-Bovine FCRLA monoclonal antibody | Bovine |
| GM-Tg-equg-SE0213-Ab-1/ GM-Tg-equg-SE0213-Ab-2 | Anti-Equine FCRLA monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0213-Ab-1/ GM-Tg-hg-SE0213-Ab-2; GM-Tg-rg-SE0213-Ab-1/ GM-Tg-rg-SE0213-Ab-2; GM-Tg-mg-SE0213-Ab-1/ GM-Tg-mg-SE0213-Ab-2; GM-Tg-cynog-SE0213-Ab-1/ GM-Tg-cynog-SE0213-Ab-2; GM-Tg-felg-SE0213-Ab-1/ GM-Tg-felg-SE0213-Ab-2; GM-Tg-cang-SE0213-Ab-1/ GM-Tg-cang-SE0213-Ab-2; GM-Tg-bovg-SE0213-Ab-1/ GM-Tg-bovg-SE0213-Ab-2; GM-Tg-equg-SE0213-Ab-1/ GM-Tg-equg-SE0213-Ab-2 |
| Products Name | Anti-FCRLA monoclonal antibody |
| Format | mab |
| Target Name | FCRLA |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FCRLA benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0213-Ag-1 | Recombinant multi-species FCRLA/ FCRL/ FCRL1 protein |
Target information
| Target ID | GM-SE0213 |
| Target Name | FCRLA |
| Gene ID | 84824,98752,304965,720016,488658,101087297,782871,100051384 |
| Gene Symbol and Synonyms | FCRL,FCRL1,FCRLA,FCRLb,FCRLc1,FCRLc2,FCRLd,FCRLe,FCRLM1,FCRLX,FCRX,FREB,FREB-like,Freb1,mFcrX,mFREB,RGD1306176 |
| Uniprot Accession | Q7L513,Q3B8P2 |
| Uniprot Entry Name | FCRLA_HUMAN,FCRLA_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000132185 |
| Target Classification | N/A |
The target: FCRLA, gene name: FCRLA, also named as FCRL, FCRL1, FCRLM1, FCRLX, FCRLb, FCRLc1, FCRLc2, FCRLd, FCRLe, FCRX, FREB. This gene encodes a protein similar to receptors for the Fc fragment of gamma immunoglobulin (IgG). These receptors, referred to as FCGRs, mediate the destruction of IgG-coated antigens and of cells induced by antibodies. This encoded protein is selectively expressed in B cells, and may be involved in their development. This protein may also be involved in the development of lymphomas. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Aug 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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