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Anti-EPGN/ ALGV3072/ EPG functional antibody
Anti-EPGN/ ALGV3072/ EPG functional antibody for cell culture, ELISA & in-vivo assay
Go to EPGN/EPGN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0181-Ab-1/ GM-Tg-hg-SE0181-Ab-2 | Anti-Human EPGN monoclonal antibody | Human |
| GM-Tg-rg-SE0181-Ab-1/ GM-Tg-rg-SE0181-Ab-2 | Anti-Rat EPGN monoclonal antibody | Rat |
| GM-Tg-mg-SE0181-Ab-1/ GM-Tg-mg-SE0181-Ab-2 | Anti-Mouse EPGN monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0181-Ab-1/ GM-Tg-cynog-SE0181-Ab-2 | Anti-Cynomolgus/ Rhesus macaque EPGN monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0181-Ab-1/ GM-Tg-felg-SE0181-Ab-2 | Anti-Feline EPGN monoclonal antibody | Feline |
| GM-Tg-cang-SE0181-Ab-1/ GM-Tg-cang-SE0181-Ab-2 | Anti-Canine EPGN monoclonal antibody | Canine |
| GM-Tg-bovg-SE0181-Ab-1/ GM-Tg-bovg-SE0181-Ab-2 | Anti-Bovine EPGN monoclonal antibody | Bovine |
| GM-Tg-equg-SE0181-Ab-1/ GM-Tg-equg-SE0181-Ab-2 | Anti-Equine EPGN monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0181-Ab-1/ GM-Tg-hg-SE0181-Ab-2; GM-Tg-rg-SE0181-Ab-1/ GM-Tg-rg-SE0181-Ab-2; GM-Tg-mg-SE0181-Ab-1/ GM-Tg-mg-SE0181-Ab-2; GM-Tg-cynog-SE0181-Ab-1/ GM-Tg-cynog-SE0181-Ab-2; GM-Tg-felg-SE0181-Ab-1/ GM-Tg-felg-SE0181-Ab-2; GM-Tg-cang-SE0181-Ab-1/ GM-Tg-cang-SE0181-Ab-2; GM-Tg-bovg-SE0181-Ab-1/ GM-Tg-bovg-SE0181-Ab-2; GM-Tg-equg-SE0181-Ab-1/ GM-Tg-equg-SE0181-Ab-2 |
| Products Name | Anti-EPGN monoclonal antibody |
| Format | mab |
| Target Name | EPGN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-EPGN benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0181-Ag-1 | Recombinant multi-species EPGN/ ALGV3072/ EPG protein |
| Cytokine | GM-Tg-g-SE0181-Ag-1 | epithelial mitogen (EPGN) protein |
Target information
| Target ID | GM-SE0181 |
| Target Name | EPGN |
| Gene ID | 255324,71920,289515,702632,611937,101081293,100295331,100050376 |
| Gene Symbol and Synonyms | 2310069M11Rik,ALGV3072,EPG,EPGN,epigen,PRO9904,RGD1560084 |
| Uniprot Accession | Q6UW88 |
| Uniprot Entry Name | EPGN_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000182585 |
| Target Classification | N/A |
The target: EPGN, gene name: EPGN, also named as ALGV3072, EPG, PRO9904. The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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