Anti-CHST7/ C6ST-2/ GST-5 functional antibody

Anti-CHST7/ C6ST-2/ GST-5 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CHST7/CHST7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0087-Ab-1/ GM-Tg-hg-SE0087-Ab-2Anti-Human CHST7 monoclonal antibodyHuman
GM-Tg-rg-SE0087-Ab-1/ GM-Tg-rg-SE0087-Ab-2Anti-Rat CHST7 monoclonal antibodyRat
GM-Tg-mg-SE0087-Ab-1/ GM-Tg-mg-SE0087-Ab-2Anti-Mouse CHST7 monoclonal antibodyMouse
GM-Tg-cynog-SE0087-Ab-1/ GM-Tg-cynog-SE0087-Ab-2Anti-Cynomolgus/ Rhesus macaque CHST7 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0087-Ab-1/ GM-Tg-felg-SE0087-Ab-2Anti-Feline CHST7 monoclonal antibodyFeline
GM-Tg-cang-SE0087-Ab-1/ GM-Tg-cang-SE0087-Ab-2Anti-Canine CHST7 monoclonal antibodyCanine
GM-Tg-bovg-SE0087-Ab-1/ GM-Tg-bovg-SE0087-Ab-2Anti-Bovine CHST7 monoclonal antibodyBovine
GM-Tg-equg-SE0087-Ab-1/ GM-Tg-equg-SE0087-Ab-2Anti-Equine CHST7 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0087-Ab-1/ GM-Tg-hg-SE0087-Ab-2; GM-Tg-rg-SE0087-Ab-1/ GM-Tg-rg-SE0087-Ab-2;
GM-Tg-mg-SE0087-Ab-1/ GM-Tg-mg-SE0087-Ab-2; GM-Tg-cynog-SE0087-Ab-1/ GM-Tg-cynog-SE0087-Ab-2;
GM-Tg-felg-SE0087-Ab-1/ GM-Tg-felg-SE0087-Ab-2; GM-Tg-cang-SE0087-Ab-1/ GM-Tg-cang-SE0087-Ab-2;
GM-Tg-bovg-SE0087-Ab-1/ GM-Tg-bovg-SE0087-Ab-2; GM-Tg-equg-SE0087-Ab-1/ GM-Tg-equg-SE0087-Ab-2
Products NameAnti-CHST7 monoclonal antibody
Formatmab
Target NameCHST7
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CHST7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0087-Ag-1Recombinant multi-species CHST7/ C6ST-2/ GST-5 protein


    Target information

    Target IDGM-SE0087
    Target NameCHST7
    Gene ID56548,60322,302302,704906,491852,101089584,540357,111771611
    Gene Symbol and Synonyms2600013M07Rik,C6ST-2,CHST7,glcNAc6ST-4,Gn6st-4,GST-5,GST5
    Uniprot AccessionQ9NS84,Q6XQG8
    Uniprot Entry NameCHST7_HUMAN,CHST7_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000147119
    Target ClassificationN/A

    The target: CHST7, gene name: CHST7, also named as C6ST-2, GST-5. This gene is a member of the Gal/GalNAc/GlcNAc (galactose/N-acetylgalactosamine/N-acetylglucosamine) 6-O-sulfotransferase (GST) family. Members of this family encode enzymes that catalyze the specific addition of sulfate groups to distinct hydroxyl and amino groups of carbohydrates. The encoded protein catalyzes the sulfation of 6-hydroxyl group of GalNAc in chondroitin. [provided by RefSeq, Aug 2013].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.