Anti-CHSTD/ CHST13/ C4ST3 functional antibody

Anti-CHSTD/ CHST13/ C4ST3 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CHST13/CHST13 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0085-Ab-1/ GM-Tg-hg-SE0085-Ab-2Anti-Human CHST13 monoclonal antibodyHuman
GM-Tg-rg-SE0085-Ab-1/ GM-Tg-rg-SE0085-Ab-2Anti-Rat CHST13 monoclonal antibodyRat
GM-Tg-mg-SE0085-Ab-1/ GM-Tg-mg-SE0085-Ab-2Anti-Mouse CHST13 monoclonal antibodyMouse
GM-Tg-cynog-SE0085-Ab-1/ GM-Tg-cynog-SE0085-Ab-2Anti-Cynomolgus/ Rhesus macaque CHST13 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0085-Ab-1/ GM-Tg-felg-SE0085-Ab-2Anti-Feline CHST13 monoclonal antibodyFeline
GM-Tg-cang-SE0085-Ab-1/ GM-Tg-cang-SE0085-Ab-2Anti-Canine CHST13 monoclonal antibodyCanine
GM-Tg-bovg-SE0085-Ab-1/ GM-Tg-bovg-SE0085-Ab-2Anti-Bovine CHST13 monoclonal antibodyBovine
GM-Tg-equg-SE0085-Ab-1/ GM-Tg-equg-SE0085-Ab-2Anti-Equine CHST13 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0085-Ab-1/ GM-Tg-hg-SE0085-Ab-2; GM-Tg-rg-SE0085-Ab-1/ GM-Tg-rg-SE0085-Ab-2;
GM-Tg-mg-SE0085-Ab-1/ GM-Tg-mg-SE0085-Ab-2; GM-Tg-cynog-SE0085-Ab-1/ GM-Tg-cynog-SE0085-Ab-2;
GM-Tg-felg-SE0085-Ab-1/ GM-Tg-felg-SE0085-Ab-2; GM-Tg-cang-SE0085-Ab-1/ GM-Tg-cang-SE0085-Ab-2;
GM-Tg-bovg-SE0085-Ab-1/ GM-Tg-bovg-SE0085-Ab-2; GM-Tg-equg-SE0085-Ab-1/ GM-Tg-equg-SE0085-Ab-2
Products NameAnti-CHST13 monoclonal antibody
Formatmab
Target NameCHST13
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CHST13 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0085-Ag-1Recombinant multi-species CHSTD/ CHST13/ C4ST3 protein


    Target information

    Target IDGM-SE0085
    Target NameCHST13
    Gene ID166012,71797,500257,716548,484618,101093089,523460,111768279
    Gene Symbol and Synonyms1110067M19Rik,C4ST-3,C4ST3,CHST13,RGD1562825
    Uniprot AccessionQ8NET6
    Uniprot Entry NameCHSTD_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000180767
    Target ClassificationN/A

    The target: CHST13, gene name: CHST13, also named as C4ST3. The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. [provided by RefSeq, Aug 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.