Anti-NUBPL/ C14orf127/ IND1 monoclonal antibody

Anti-NUBPL/ C14orf127/ IND1 antibody for FACS & in-vivo assay

Target products collectionGo to NUBPL/NUBPL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2593-Ab-1/ GM-Tg-hg-MP2593-Ab-2Anti-Human NUBPL monoclonal antibodyHuman
GM-Tg-rg-MP2593-Ab-1/ GM-Tg-rg-MP2593-Ab-2Anti-Rat NUBPL monoclonal antibodyRat
GM-Tg-mg-MP2593-Ab-1/ GM-Tg-mg-MP2593-Ab-2Anti-Mouse NUBPL monoclonal antibodyMouse
GM-Tg-cynog-MP2593-Ab-1/ GM-Tg-cynog-MP2593-Ab-2Anti-Cynomolgus/ Rhesus macaque NUBPL monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2593-Ab-1/ GM-Tg-felg-MP2593-Ab-2Anti-Feline NUBPL monoclonal antibodyFeline
GM-Tg-cang-MP2593-Ab-1/ GM-Tg-cang-MP2593-Ab-2Anti-Canine NUBPL monoclonal antibodyCanine
GM-Tg-bovg-MP2593-Ab-1/ GM-Tg-bovg-MP2593-Ab-2Anti-Bovine NUBPL monoclonal antibodyBovine
GM-Tg-equg-MP2593-Ab-1/ GM-Tg-equg-MP2593-Ab-2Anti-Equine NUBPL monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2593-Ab-1/ GM-Tg-hg-MP2593-Ab-2; GM-Tg-rg-MP2593-Ab-1/ GM-Tg-rg-MP2593-Ab-2;
GM-Tg-mg-MP2593-Ab-1/ GM-Tg-mg-MP2593-Ab-2; GM-Tg-cynog-MP2593-Ab-1/ GM-Tg-cynog-MP2593-Ab-2;
GM-Tg-felg-MP2593-Ab-1/ GM-Tg-felg-MP2593-Ab-2; GM-Tg-cang-MP2593-Ab-1/ GM-Tg-cang-MP2593-Ab-2;
GM-Tg-bovg-MP2593-Ab-1/ GM-Tg-bovg-MP2593-Ab-2; GM-Tg-equg-MP2593-Ab-1/ GM-Tg-equg-MP2593-Ab-2
Products NameAnti-NUBPL monoclonal antibody
Formatmab
Target NameNUBPL
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-NUBPL benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species NUBPL/ C14orf127/ IND1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2593
    Target NameNUBPL
    Gene ID80224,76826,299008,717011,609340,101088001,614641,100056157
    Gene Symbol and Synonyms2410170E07Rik,C14orf127,huInd1,IND1,MC1DN21,NUBPL,RGD1307232
    Uniprot AccessionQ8TB37
    Uniprot Entry NameNUBPL_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000151413
    Target ClassificationN/A

    The target: NUBPL, gene name: NUBPL, also named as C14orf127, IND1, huInd1. This gene encodes a member of the Mrp/NBP35 ATP-binding proteins family. The encoded protein is required for the assembly of the respiratory chain NADH dehydrogenase (complex I), an oligomeric enzymatic complex located in the inner mitochondrial membrane. Mutations in this gene cause mitochondrial complex I deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.