Anti-CEMIP/ CCSP1/ HYBID monoclonal antibody

Anti-CEMIP/ CCSP1/ HYBID antibody for FACS & in-vivo assay

Target products collectionGo to CEMIP/CEMIP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2428-Ab-1/ GM-Tg-hg-MP2428-Ab-2Anti-Human CEMIP monoclonal antibodyHuman
GM-Tg-rg-MP2428-Ab-1/ GM-Tg-rg-MP2428-Ab-2Anti-Rat CEMIP monoclonal antibodyRat
GM-Tg-mg-MP2428-Ab-1/ GM-Tg-mg-MP2428-Ab-2Anti-Mouse CEMIP monoclonal antibodyMouse
GM-Tg-cynog-MP2428-Ab-1/ GM-Tg-cynog-MP2428-Ab-2Anti-Cynomolgus/ Rhesus macaque CEMIP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2428-Ab-1/ GM-Tg-felg-MP2428-Ab-2Anti-Feline CEMIP monoclonal antibodyFeline
GM-Tg-cang-MP2428-Ab-1/ GM-Tg-cang-MP2428-Ab-2Anti-Canine CEMIP monoclonal antibodyCanine
GM-Tg-bovg-MP2428-Ab-1/ GM-Tg-bovg-MP2428-Ab-2Anti-Bovine CEMIP monoclonal antibodyBovine
GM-Tg-equg-MP2428-Ab-1/ GM-Tg-equg-MP2428-Ab-2Anti-Equine CEMIP monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2428-Ab-1/ GM-Tg-hg-MP2428-Ab-2; GM-Tg-rg-MP2428-Ab-1/ GM-Tg-rg-MP2428-Ab-2;
GM-Tg-mg-MP2428-Ab-1/ GM-Tg-mg-MP2428-Ab-2; GM-Tg-cynog-MP2428-Ab-1/ GM-Tg-cynog-MP2428-Ab-2;
GM-Tg-felg-MP2428-Ab-1/ GM-Tg-felg-MP2428-Ab-2; GM-Tg-cang-MP2428-Ab-1/ GM-Tg-cang-MP2428-Ab-2;
GM-Tg-bovg-MP2428-Ab-1/ GM-Tg-bovg-MP2428-Ab-2; GM-Tg-equg-MP2428-Ab-1/ GM-Tg-equg-MP2428-Ab-2
Products NameAnti-CEMIP monoclonal antibody
Formatmab
Target NameCEMIP
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CEMIP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CEMIP/ CCSP1/ HYBID VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2428
    Target NameCEMIP
    Gene ID57214,80982,308797,717880,488766,101094181,519047,100053052
    Gene Symbol and Synonyms12H19.01.T7,6330404C01Rik,9930013L23Rik,CCSP1,CEMIP,CEMIP1,HYBID,KIAA1199,Q9ULM1,RGD1305254,™EM2L
    Uniprot AccessionQ8WUJ3
    Uniprot Entry NameCEMIP_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000103888
    Target ClassificationN/A

    The target: CEMIP, gene name: CEMIP, also named as CCSP1, HYBID, KIAA1199, ™EM2L. Enables several functions, including clathrin heavy chain binding activity; hyaluronic acid binding activity; and hyalurononglucosaminidase activity. Involved in several processes, including hyaluronan catabolic process; positive regulation of protein phosphorylation; and positive regulation of transport. Located in clathrin-coated endocytic vesicle; endoplasmic reticulum; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.