Anti-GBP1 monoclonal antibody

Anti-GBP1 antibody for FACS & in-vivo assay

Target products collectionGo to GBP1/GBP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2397-Ab-1/ GM-Tg-hg-MP2397-Ab-2Anti-Human GBP1 monoclonal antibodyHuman
GM-Tg-rg-MP2397-Ab-1/ GM-Tg-rg-MP2397-Ab-2Anti-Rat GBP1 monoclonal antibodyRat
GM-Tg-mg-MP2397-Ab-1/ GM-Tg-mg-MP2397-Ab-2Anti-Mouse GBP1 monoclonal antibodyMouse
GM-Tg-cynog-MP2397-Ab-1/ GM-Tg-cynog-MP2397-Ab-2Anti-Cynomolgus/ Rhesus macaque GBP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2397-Ab-1/ GM-Tg-felg-MP2397-Ab-2Anti-Feline GBP1 monoclonal antibodyFeline
GM-Tg-cang-MP2397-Ab-1/ GM-Tg-cang-MP2397-Ab-2Anti-Canine GBP1 monoclonal antibodyCanine
GM-Tg-bovg-MP2397-Ab-1/ GM-Tg-bovg-MP2397-Ab-2Anti-Bovine GBP1 monoclonal antibodyBovine
GM-Tg-equg-MP2397-Ab-1/ GM-Tg-equg-MP2397-Ab-2Anti-Equine GBP1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2397-Ab-1/ GM-Tg-hg-MP2397-Ab-2; GM-Tg-rg-MP2397-Ab-1/ GM-Tg-rg-MP2397-Ab-2;
GM-Tg-mg-MP2397-Ab-1/ GM-Tg-mg-MP2397-Ab-2; GM-Tg-cynog-MP2397-Ab-1/ GM-Tg-cynog-MP2397-Ab-2;
GM-Tg-felg-MP2397-Ab-1/ GM-Tg-felg-MP2397-Ab-2; GM-Tg-cang-MP2397-Ab-1/ GM-Tg-cang-MP2397-Ab-2;
GM-Tg-bovg-MP2397-Ab-1/ GM-Tg-bovg-MP2397-Ab-2; GM-Tg-equg-MP2397-Ab-1/ GM-Tg-equg-MP2397-Ab-2
Products NameAnti-GBP1 monoclonal antibody
Formatmab
Target NameGBP1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GBP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GBP1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLV000305human GBP1 Lentivirus plasmid
    ORF Viral VectorvGMLV000497human GBP1 Lentivirus particle
    ORF Viral VectorpGMLV000497human GBP1 Lentivirus plasmid
    ORF Viral VectorvGMLV000305human GBP1 Lentivirus particle


    Target information

    Target IDGM-MP2397
    Target NameGBP1
    Gene ID2633
    Gene Symbol and SynonymsGBP1,hGBP1
    Uniprot AccessionP32455
    Uniprot Entry NameGBP1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000117228
    Target ClassificationN/A

    The target: GBP1, gene name: GBP1, also named as . Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.