Anti-UBP4/ USP4/ UNP monoclonal antibody

Anti-UBP4/ USP4/ UNP antibody for FACS & in-vivo assay

Target products collectionGo to USP4/USP4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2377-Ab-1/ GM-Tg-hg-MP2377-Ab-2Anti-Human USP4 monoclonal antibodyHuman
GM-Tg-rg-MP2377-Ab-1/ GM-Tg-rg-MP2377-Ab-2Anti-Rat USP4 monoclonal antibodyRat
GM-Tg-mg-MP2377-Ab-1/ GM-Tg-mg-MP2377-Ab-2Anti-Mouse USP4 monoclonal antibodyMouse
GM-Tg-cynog-MP2377-Ab-1/ GM-Tg-cynog-MP2377-Ab-2Anti-Cynomolgus/ Rhesus macaque USP4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2377-Ab-1/ GM-Tg-felg-MP2377-Ab-2Anti-Feline USP4 monoclonal antibodyFeline
GM-Tg-cang-MP2377-Ab-1/ GM-Tg-cang-MP2377-Ab-2Anti-Canine USP4 monoclonal antibodyCanine
GM-Tg-bovg-MP2377-Ab-1/ GM-Tg-bovg-MP2377-Ab-2Anti-Bovine USP4 monoclonal antibodyBovine
GM-Tg-equg-MP2377-Ab-1/ GM-Tg-equg-MP2377-Ab-2Anti-Equine USP4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2377-Ab-1/ GM-Tg-hg-MP2377-Ab-2; GM-Tg-rg-MP2377-Ab-1/ GM-Tg-rg-MP2377-Ab-2;
GM-Tg-mg-MP2377-Ab-1/ GM-Tg-mg-MP2377-Ab-2; GM-Tg-cynog-MP2377-Ab-1/ GM-Tg-cynog-MP2377-Ab-2;
GM-Tg-felg-MP2377-Ab-1/ GM-Tg-felg-MP2377-Ab-2; GM-Tg-cang-MP2377-Ab-1/ GM-Tg-cang-MP2377-Ab-2;
GM-Tg-bovg-MP2377-Ab-1/ GM-Tg-bovg-MP2377-Ab-2; GM-Tg-equg-MP2377-Ab-1/ GM-Tg-equg-MP2377-Ab-2
Products NameAnti-USP4 monoclonal antibody
Formatmab
Target NameUSP4
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-USP4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species UBP4/ USP4/ UNP VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2377
    Target NameUSP4
    Gene ID7375,22258,290864,706930,476624,101083327,508042,100053443
    Gene Symbol and SynonymsF730026I20Rik,mKIAA4155,UNP,Unph,USP4
    Uniprot AccessionQ13107,B2GUZ1,A6QR55
    Uniprot Entry NameUBP4_HUMAN,UBP4_RAT,UBP4_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000114316
    Target ClassificationN/A

    The target: USP4, gene name: USP4, also named as UNP, Unph. The protein encoded by this gene is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. The encoded protein shuttles between the nucleus and cytoplasm and is involved in maintaining operational fidelity in the endoplasmic reticulum. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.