Anti-UBAC1/ GBDR1/ KPC2 monoclonal antibody

Anti-UBAC1/ GBDR1/ KPC2 antibody for FACS & in-vivo assay

Target products collectionGo to UBAC1/UBAC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2369-Ab-1/ GM-Tg-hg-MP2369-Ab-2Anti-Human UBAC1 monoclonal antibodyHuman
GM-Tg-rg-MP2369-Ab-1/ GM-Tg-rg-MP2369-Ab-2Anti-Rat UBAC1 monoclonal antibodyRat
GM-Tg-mg-MP2369-Ab-1/ GM-Tg-mg-MP2369-Ab-2Anti-Mouse UBAC1 monoclonal antibodyMouse
GM-Tg-cynog-MP2369-Ab-1/ GM-Tg-cynog-MP2369-Ab-2Anti-Cynomolgus/ Rhesus macaque UBAC1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2369-Ab-1/ GM-Tg-felg-MP2369-Ab-2Anti-Feline UBAC1 monoclonal antibodyFeline
GM-Tg-cang-MP2369-Ab-1/ GM-Tg-cang-MP2369-Ab-2Anti-Canine UBAC1 monoclonal antibodyCanine
GM-Tg-bovg-MP2369-Ab-1/ GM-Tg-bovg-MP2369-Ab-2Anti-Bovine UBAC1 monoclonal antibodyBovine
GM-Tg-equg-MP2369-Ab-1/ GM-Tg-equg-MP2369-Ab-2Anti-Equine UBAC1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2369-Ab-1/ GM-Tg-hg-MP2369-Ab-2; GM-Tg-rg-MP2369-Ab-1/ GM-Tg-rg-MP2369-Ab-2;
GM-Tg-mg-MP2369-Ab-1/ GM-Tg-mg-MP2369-Ab-2; GM-Tg-cynog-MP2369-Ab-1/ GM-Tg-cynog-MP2369-Ab-2;
GM-Tg-felg-MP2369-Ab-1/ GM-Tg-felg-MP2369-Ab-2; GM-Tg-cang-MP2369-Ab-1/ GM-Tg-cang-MP2369-Ab-2;
GM-Tg-bovg-MP2369-Ab-1/ GM-Tg-bovg-MP2369-Ab-2; GM-Tg-equg-MP2369-Ab-1/ GM-Tg-equg-MP2369-Ab-2
Products NameAnti-UBAC1 monoclonal antibody
Formatmab
Target NameUBAC1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-UBAC1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species UBAC1/ GBDR1/ KPC2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2369
    Target NameUBAC1
    Gene ID10422,98766,362087,711250,491256,101091911,613652,100068463
    Gene Symbol and Synonyms1110033G07Rik,GBDR1,Gdbr1,KPC2,UBAC1,UBADC1
    Uniprot AccessionQ9BSL1,Q5XIR9
    Uniprot Entry NameUBAC1_HUMAN,UBAC1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000130560
    Target ClassificationN/A

    The target: UBAC1, gene name: UBAC1, also named as GBDR1, KPC2, UBADC1. Predicted to be involved in protein ubiquitination. Located in Golgi apparatus; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.