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Anti-STABP/ STAMBP/ AMSH monoclonal antibody
Anti-STABP/ STAMBP/ AMSH antibody for FACS & in-vivo assay
Go to STAMBP/STAMBP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2338-Ab-1/ GM-Tg-hg-MP2338-Ab-2 | Anti-Human STAMBP monoclonal antibody | Human |
| GM-Tg-rg-MP2338-Ab-1/ GM-Tg-rg-MP2338-Ab-2 | Anti-Rat STAMBP monoclonal antibody | Rat |
| GM-Tg-mg-MP2338-Ab-1/ GM-Tg-mg-MP2338-Ab-2 | Anti-Mouse STAMBP monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2338-Ab-1/ GM-Tg-cynog-MP2338-Ab-2 | Anti-Cynomolgus/ Rhesus macaque STAMBP monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2338-Ab-1/ GM-Tg-felg-MP2338-Ab-2 | Anti-Feline STAMBP monoclonal antibody | Feline |
| GM-Tg-cang-MP2338-Ab-1/ GM-Tg-cang-MP2338-Ab-2 | Anti-Canine STAMBP monoclonal antibody | Canine |
| GM-Tg-bovg-MP2338-Ab-1/ GM-Tg-bovg-MP2338-Ab-2 | Anti-Bovine STAMBP monoclonal antibody | Bovine |
| GM-Tg-equg-MP2338-Ab-1/ GM-Tg-equg-MP2338-Ab-2 | Anti-Equine STAMBP monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2338-Ab-1/ GM-Tg-hg-MP2338-Ab-2; GM-Tg-rg-MP2338-Ab-1/ GM-Tg-rg-MP2338-Ab-2; GM-Tg-mg-MP2338-Ab-1/ GM-Tg-mg-MP2338-Ab-2; GM-Tg-cynog-MP2338-Ab-1/ GM-Tg-cynog-MP2338-Ab-2; GM-Tg-felg-MP2338-Ab-1/ GM-Tg-felg-MP2338-Ab-2; GM-Tg-cang-MP2338-Ab-1/ GM-Tg-cang-MP2338-Ab-2; GM-Tg-bovg-MP2338-Ab-1/ GM-Tg-bovg-MP2338-Ab-2; GM-Tg-equg-MP2338-Ab-1/ GM-Tg-equg-MP2338-Ab-2 |
| Products Name | Anti-STAMBP monoclonal antibody |
| Format | mab |
| Target Name | STAMBP |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-STAMBP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species STABP/ STAMBP/ AMSH VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-MP2338-Ag-1 | STAM binding protein (STAMBP) protein |
Target information
| Target ID | GM-MP2338 |
| Target Name | STAMBP |
| Gene ID | 10617,70527,171565,714562,100684058,101082485,532672,100049814 |
| Gene Symbol and Synonyms | 5330424L14Rik,5730422L11Rik,AMSH,MICCAP,mKIAA4198,STAMBP |
| Uniprot Accession | O95630,Q8R424 |
| Uniprot Entry Name | STABP_HUMAN,STABP_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000124356 |
| Target Classification | N/A |
The target: STAMBP, gene name: STAMBP, also named as AMSH, MICCAP. Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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