Anti-RASF3/ RASSF3/ RASSF5 monoclonal antibody

Anti-RASF3/ RASSF3/ RASSF5 antibody for FACS & in-vivo assay

Target products collectionGo to RASSF3/RASSF3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2289-Ab-1/ GM-Tg-hg-MP2289-Ab-2Anti-Human RASSF3 monoclonal antibodyHuman
GM-Tg-rg-MP2289-Ab-1/ GM-Tg-rg-MP2289-Ab-2Anti-Rat RASSF3 monoclonal antibodyRat
GM-Tg-mg-MP2289-Ab-1/ GM-Tg-mg-MP2289-Ab-2Anti-Mouse RASSF3 monoclonal antibodyMouse
GM-Tg-cynog-MP2289-Ab-1/ GM-Tg-cynog-MP2289-Ab-2Anti-Cynomolgus/ Rhesus macaque RASSF3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2289-Ab-1/ GM-Tg-felg-MP2289-Ab-2Anti-Feline RASSF3 monoclonal antibodyFeline
GM-Tg-cang-MP2289-Ab-1/ GM-Tg-cang-MP2289-Ab-2Anti-Canine RASSF3 monoclonal antibodyCanine
GM-Tg-bovg-MP2289-Ab-1/ GM-Tg-bovg-MP2289-Ab-2Anti-Bovine RASSF3 monoclonal antibodyBovine
GM-Tg-equg-MP2289-Ab-1/ GM-Tg-equg-MP2289-Ab-2Anti-Equine RASSF3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2289-Ab-1/ GM-Tg-hg-MP2289-Ab-2; GM-Tg-rg-MP2289-Ab-1/ GM-Tg-rg-MP2289-Ab-2;
GM-Tg-mg-MP2289-Ab-1/ GM-Tg-mg-MP2289-Ab-2; GM-Tg-cynog-MP2289-Ab-1/ GM-Tg-cynog-MP2289-Ab-2;
GM-Tg-felg-MP2289-Ab-1/ GM-Tg-felg-MP2289-Ab-2; GM-Tg-cang-MP2289-Ab-1/ GM-Tg-cang-MP2289-Ab-2;
GM-Tg-bovg-MP2289-Ab-1/ GM-Tg-bovg-MP2289-Ab-2; GM-Tg-equg-MP2289-Ab-1/ GM-Tg-equg-MP2289-Ab-2
Products NameAnti-RASSF3 monoclonal antibody
Formatmab
Target NameRASSF3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-RASSF3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species RASF3/ RASSF3/ RASSF5 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm004020mouse Rassf3 Lentivirus plasmid
    ORF Viral VectorvGMLPm004020mouse Rassf3 Lentivirus particle


    Target information

    Target IDGM-MP2289
    Target NameRASSF3
    Gene ID283349,192678,362886,715339,608312,101087934,536808,100051721
    Gene Symbol and SynonymsRASSF3,RASSF5
    Uniprot AccessionQ86WH2
    Uniprot Entry NameRASF3_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000153179
    Target ClassificationN/A

    The target: RASSF3, gene name: RASSF3, also named as RASSF5. The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM, Jul 2003].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.