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Anti-RBGPR/ RAB3GAP2/ RAB3-GAP150 monoclonal antibody
Anti-RBGPR/ RAB3GAP2/ RAB3-GAP150 antibody for FACS & in-vivo assay
Go to RAB3GAP2/RAB3GAP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2277-Ab-1/ GM-Tg-hg-MP2277-Ab-2 | Anti-Human RAB3GAP2 monoclonal antibody | Human |
| GM-Tg-rg-MP2277-Ab-1/ GM-Tg-rg-MP2277-Ab-2 | Anti-Rat RAB3GAP2 monoclonal antibody | Rat |
| GM-Tg-mg-MP2277-Ab-1/ GM-Tg-mg-MP2277-Ab-2 | Anti-Mouse RAB3GAP2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2277-Ab-1/ GM-Tg-cynog-MP2277-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RAB3GAP2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2277-Ab-1/ GM-Tg-felg-MP2277-Ab-2 | Anti-Feline RAB3GAP2 monoclonal antibody | Feline |
| GM-Tg-cang-MP2277-Ab-1/ GM-Tg-cang-MP2277-Ab-2 | Anti-Canine RAB3GAP2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2277-Ab-1/ GM-Tg-bovg-MP2277-Ab-2 | Anti-Bovine RAB3GAP2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2277-Ab-1/ GM-Tg-equg-MP2277-Ab-2 | Anti-Equine RAB3GAP2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2277-Ab-1/ GM-Tg-hg-MP2277-Ab-2; GM-Tg-rg-MP2277-Ab-1/ GM-Tg-rg-MP2277-Ab-2; GM-Tg-mg-MP2277-Ab-1/ GM-Tg-mg-MP2277-Ab-2; GM-Tg-cynog-MP2277-Ab-1/ GM-Tg-cynog-MP2277-Ab-2; GM-Tg-felg-MP2277-Ab-1/ GM-Tg-felg-MP2277-Ab-2; GM-Tg-cang-MP2277-Ab-1/ GM-Tg-cang-MP2277-Ab-2; GM-Tg-bovg-MP2277-Ab-1/ GM-Tg-bovg-MP2277-Ab-2; GM-Tg-equg-MP2277-Ab-1/ GM-Tg-equg-MP2277-Ab-2 |
| Products Name | Anti-RAB3GAP2 monoclonal antibody |
| Format | mab |
| Target Name | RAB3GAP2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RAB3GAP2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species RBGPR/ RAB3GAP2/ RAB3-GAP150 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2277 |
| Target Name | RAB3GAP2 |
| Gene ID | 25782,98732,289350,706252,478964,101098767,539227,100049979 |
| Gene Symbol and Synonyms | 1110059F07Rik,2010002H18Rik,5830469C09,MARTS1,mKIAA0839,p150,RAB3-GAP150,RAB3GAP150,RAB3GAP2,RGD1311518,SPG69,WARBM2 |
| Uniprot Accession | Q9H2M9,Q5U1Z0 |
| Uniprot Entry Name | RBGPR_HUMAN,RBGPR_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000118873 |
| Target Classification | N/A |
The target: RAB3GAP2, gene name: RAB3GAP2, also named as RAB3-GAP150, RAB3GAP150, SPG69, WARBM2, p150. The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.[provided by RefSeq, Oct 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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