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Anti-PI42A/ PIP4K2A/ PI5P4KA monoclonal antibody
Anti-PI42A/ PIP4K2A/ PI5P4KA antibody for FACS & in-vivo assay
Go to PIP4K2A/PIP4K2A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2243-Ab-1/ GM-Tg-hg-MP2243-Ab-2 | Anti-Human PIP4K2A monoclonal antibody | Human |
| GM-Tg-rg-MP2243-Ab-1/ GM-Tg-rg-MP2243-Ab-2 | Anti-Rat PIP4K2A monoclonal antibody | Rat |
| GM-Tg-mg-MP2243-Ab-1/ GM-Tg-mg-MP2243-Ab-2 | Anti-Mouse PIP4K2A monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2243-Ab-1/ GM-Tg-cynog-MP2243-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PIP4K2A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2243-Ab-1/ GM-Tg-felg-MP2243-Ab-2 | Anti-Feline PIP4K2A monoclonal antibody | Feline |
| GM-Tg-cang-MP2243-Ab-1/ GM-Tg-cang-MP2243-Ab-2 | Anti-Canine PIP4K2A monoclonal antibody | Canine |
| GM-Tg-bovg-MP2243-Ab-1/ GM-Tg-bovg-MP2243-Ab-2 | Anti-Bovine PIP4K2A monoclonal antibody | Bovine |
| GM-Tg-equg-MP2243-Ab-1/ GM-Tg-equg-MP2243-Ab-2 | Anti-Equine PIP4K2A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2243-Ab-1/ GM-Tg-hg-MP2243-Ab-2; GM-Tg-rg-MP2243-Ab-1/ GM-Tg-rg-MP2243-Ab-2; GM-Tg-mg-MP2243-Ab-1/ GM-Tg-mg-MP2243-Ab-2; GM-Tg-cynog-MP2243-Ab-1/ GM-Tg-cynog-MP2243-Ab-2; GM-Tg-felg-MP2243-Ab-1/ GM-Tg-felg-MP2243-Ab-2; GM-Tg-cang-MP2243-Ab-1/ GM-Tg-cang-MP2243-Ab-2; GM-Tg-bovg-MP2243-Ab-1/ GM-Tg-bovg-MP2243-Ab-2; GM-Tg-equg-MP2243-Ab-1/ GM-Tg-equg-MP2243-Ab-2 |
| Products Name | Anti-PIP4K2A monoclonal antibody |
| Format | mab |
| Target Name | PIP4K2A |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PIP4K2A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species PI42A/ PIP4K2A/ PI5P4KA VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP003965 | human PIP4K2A Lentivirus particle |
| ORF Viral Vector | vGMLV000227 | human PIP4K2A Lentivirus particle |
| ORF Viral Vector | pGMLP003965 | human PIP4K2A Lentivirus plasmid |
| ORF Viral Vector | pGMLV000227 | human PIP4K2A Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002624 | mouse Pip4k2a Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002624 | mouse Pip4k2a Lentivirus particle |
Target information
| Target ID | GM-MP2243 |
| Target Name | PIP4K2A |
| Gene ID | 5305,18718,116723,710724,608414,101096576,533289,100066733 |
| Gene Symbol and Synonyms | PI5P4KA,PIP4K2A,PIP5K2A,PIP5KII-alpha,PIP5KIIA,PIPK |
| Uniprot Accession | P48426,Q9R0I8 |
| Uniprot Entry Name | PI42A_HUMAN,PI42A_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000150867 |
| Target Classification | N/A |
The target: PIP4K2A, gene name: PIP4K2A, also named as PI5P4KA, PIP5K2A, PIP5KII-alpha, PIP5KIIA, PIPK. Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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