Anti-PALM2-AKAP2/ AKAP2 monoclonal antibody

Anti-PALM2-AKAP2/ AKAP2 antibody for FACS & in-vivo assay

Target products collectionGo to PALM2-AKAP2/PALM2-AKAP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2232-Ab-1/ GM-Tg-hg-MP2232-Ab-2Anti-Human PALM2-AKAP2 monoclonal antibodyHuman
GM-Tg-rg-MP2232-Ab-1/ GM-Tg-rg-MP2232-Ab-2Anti-Rat PALM2-AKAP2 monoclonal antibodyRat
GM-Tg-mg-MP2232-Ab-1/ GM-Tg-mg-MP2232-Ab-2Anti-Mouse PALM2-AKAP2 monoclonal antibodyMouse
GM-Tg-cynog-MP2232-Ab-1/ GM-Tg-cynog-MP2232-Ab-2Anti-Cynomolgus/ Rhesus macaque PALM2-AKAP2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2232-Ab-1/ GM-Tg-felg-MP2232-Ab-2Anti-Feline PALM2-AKAP2 monoclonal antibodyFeline
GM-Tg-cang-MP2232-Ab-1/ GM-Tg-cang-MP2232-Ab-2Anti-Canine PALM2-AKAP2 monoclonal antibodyCanine
GM-Tg-bovg-MP2232-Ab-1/ GM-Tg-bovg-MP2232-Ab-2Anti-Bovine PALM2-AKAP2 monoclonal antibodyBovine
GM-Tg-equg-MP2232-Ab-1/ GM-Tg-equg-MP2232-Ab-2Anti-Equine PALM2-AKAP2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2232-Ab-1/ GM-Tg-hg-MP2232-Ab-2; GM-Tg-rg-MP2232-Ab-1/ GM-Tg-rg-MP2232-Ab-2;
GM-Tg-mg-MP2232-Ab-1/ GM-Tg-mg-MP2232-Ab-2; GM-Tg-cynog-MP2232-Ab-1/ GM-Tg-cynog-MP2232-Ab-2;
GM-Tg-felg-MP2232-Ab-1/ GM-Tg-felg-MP2232-Ab-2; GM-Tg-cang-MP2232-Ab-1/ GM-Tg-cang-MP2232-Ab-2;
GM-Tg-bovg-MP2232-Ab-1/ GM-Tg-bovg-MP2232-Ab-2; GM-Tg-equg-MP2232-Ab-1/ GM-Tg-equg-MP2232-Ab-2
Products NameAnti-PALM2-AKAP2 monoclonal antibody
Formatmab
Target NamePALM2-AKAP2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PALM2-AKAP2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PALM2-AKAP2/ AKAP2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2232
    Target NamePALM2-AKAP2
    Gene ID445815,677884,709841,481660,105261111,100532750,100630682
    Gene Symbol and Synonyms53-H12,AA959716,AI649048,AKAP-2,AKAP-KL,AKAP2,AKAPKL,B130066I24,B230340M18Rik,Gm20459,MISP2,Pakap,PALM2,PALM2-AKAP2,PALM2AKAP2,pEN70,PRKA2,R75368
    Uniprot AccessionN/A
    Uniprot Entry Name
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000157654
    Target ClassificationN/A

    The target: PALM2-AKAP2, gene name: PALM2-AKAP2, also named as AKAP2. This gene belongs to the paralemmin downstream gene (PDG) family defined in PMID:22855693. Paralemmin downstream genes may have evolved contiguously with the paralemmin genes and are associated with other paralemmin paralogs in humans and several other taxa. The gene encodes three distinct protein isoforms, the PALM2 isoform, the AKAP2 isoform and the PALM2-AKAP2 isoform. The biological significance of the PALM2-AKAP2 isoforms is yet unknown. Earlier, PALM2 and AKAP2 were annotated as separate genes and PALM2-AKAP2 was annotated as a readthrough gene. [provided by RefSeq, May 2019].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.