Anti-GAPD1/ GAPVD1/ GAPEX5 monoclonal antibody

Anti-GAPD1/ GAPVD1/ GAPEX5 antibody for FACS & in-vivo assay

Target products collectionGo to GAPVD1/GAPVD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2136-Ab-1/ GM-Tg-hg-MP2136-Ab-2Anti-Human GAPVD1 monoclonal antibodyHuman
GM-Tg-rg-MP2136-Ab-1/ GM-Tg-rg-MP2136-Ab-2Anti-Rat GAPVD1 monoclonal antibodyRat
GM-Tg-mg-MP2136-Ab-1/ GM-Tg-mg-MP2136-Ab-2Anti-Mouse GAPVD1 monoclonal antibodyMouse
GM-Tg-cynog-MP2136-Ab-1/ GM-Tg-cynog-MP2136-Ab-2Anti-Cynomolgus/ Rhesus macaque GAPVD1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2136-Ab-1/ GM-Tg-felg-MP2136-Ab-2Anti-Feline GAPVD1 monoclonal antibodyFeline
GM-Tg-cang-MP2136-Ab-1/ GM-Tg-cang-MP2136-Ab-2Anti-Canine GAPVD1 monoclonal antibodyCanine
GM-Tg-bovg-MP2136-Ab-1/ GM-Tg-bovg-MP2136-Ab-2Anti-Bovine GAPVD1 monoclonal antibodyBovine
GM-Tg-equg-MP2136-Ab-1/ GM-Tg-equg-MP2136-Ab-2Anti-Equine GAPVD1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2136-Ab-1/ GM-Tg-hg-MP2136-Ab-2; GM-Tg-rg-MP2136-Ab-1/ GM-Tg-rg-MP2136-Ab-2;
GM-Tg-mg-MP2136-Ab-1/ GM-Tg-mg-MP2136-Ab-2; GM-Tg-cynog-MP2136-Ab-1/ GM-Tg-cynog-MP2136-Ab-2;
GM-Tg-felg-MP2136-Ab-1/ GM-Tg-felg-MP2136-Ab-2; GM-Tg-cang-MP2136-Ab-1/ GM-Tg-cang-MP2136-Ab-2;
GM-Tg-bovg-MP2136-Ab-1/ GM-Tg-bovg-MP2136-Ab-2; GM-Tg-equg-MP2136-Ab-1/ GM-Tg-equg-MP2136-Ab-2
Products NameAnti-GAPVD1 monoclonal antibody
Formatmab
Target NameGAPVD1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GAPVD1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GAPD1/ GAPVD1/ GAPEX5 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2136
    Target NameGAPVD1
    Gene ID26130,66691,311880,712449,480725,101084144,539646,100070862
    Gene Symbol and Synonyms2010005B09Rik,4432404J10Rik,GAPex-5,GAPEX5,GAPVD1,mKIAA1521,RAP6,RGD1307479,RME-6
    Uniprot AccessionQ14C86,A5D794
    Uniprot Entry NameGAPD1_HUMAN,GAPD1_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000165219
    Target ClassificationN/A

    The target: GAPVD1, gene name: GAPVD1, also named as GAPEX5, GAPex-5, RAP6. Enables GTPase activating protein binding activity and guanyl-nucleotide exchange factor activity. Involved in regulation of protein transport. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.