Anti-NIBA1/ FAM129A/ C1orf24 monoclonal antibody

Anti-NIBA1/ FAM129A/ C1orf24 antibody for FACS & in-vivo assay

Target products collectionGo to FAM129A/FAM129A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2118-Ab-1/ GM-Tg-hg-MP2118-Ab-2Anti-Human FAM129A monoclonal antibodyHuman
GM-Tg-rg-MP2118-Ab-1/ GM-Tg-rg-MP2118-Ab-2Anti-Rat FAM129A monoclonal antibodyRat
GM-Tg-mg-MP2118-Ab-1/ GM-Tg-mg-MP2118-Ab-2Anti-Mouse FAM129A monoclonal antibodyMouse
GM-Tg-cynog-MP2118-Ab-1/ GM-Tg-cynog-MP2118-Ab-2Anti-Cynomolgus/ Rhesus macaque FAM129A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2118-Ab-1/ GM-Tg-felg-MP2118-Ab-2Anti-Feline FAM129A monoclonal antibodyFeline
GM-Tg-cang-MP2118-Ab-1/ GM-Tg-cang-MP2118-Ab-2Anti-Canine FAM129A monoclonal antibodyCanine
GM-Tg-bovg-MP2118-Ab-1/ GM-Tg-bovg-MP2118-Ab-2Anti-Bovine FAM129A monoclonal antibodyBovine
GM-Tg-equg-MP2118-Ab-1/ GM-Tg-equg-MP2118-Ab-2Anti-Equine FAM129A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2118-Ab-1/ GM-Tg-hg-MP2118-Ab-2; GM-Tg-rg-MP2118-Ab-1/ GM-Tg-rg-MP2118-Ab-2;
GM-Tg-mg-MP2118-Ab-1/ GM-Tg-mg-MP2118-Ab-2; GM-Tg-cynog-MP2118-Ab-1/ GM-Tg-cynog-MP2118-Ab-2;
GM-Tg-felg-MP2118-Ab-1/ GM-Tg-felg-MP2118-Ab-2; GM-Tg-cang-MP2118-Ab-1/ GM-Tg-cang-MP2118-Ab-2;
GM-Tg-bovg-MP2118-Ab-1/ GM-Tg-bovg-MP2118-Ab-2; GM-Tg-equg-MP2118-Ab-1/ GM-Tg-equg-MP2118-Ab-2
Products NameAnti-FAM129A monoclonal antibody
Formatmab
Target NameFAM129A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-FAM129A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species NIBA1/ FAM129A/ C1orf24 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2118
    Target NameFAM129A
    Gene ID116496,63913,63912,714427,480041,101086940,614787,100055982
    Gene Symbol and SynonymsC1orf24,FAM129A,GIG39,NIBAN,NIBAN1
    Uniprot AccessionQ9BZQ8,Q9ESN0
    Uniprot Entry NameNIBA1_HUMAN,NIBA1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000135842
    Target ClassificationN/A

    The target: FAM129A, gene name: FAM129A, also named as C1orf24, GIG39, NIBAN. This gene encodes a member of the family with sequence similarity 129 protein family. This gene is highly expressed in several cancer cells and may serve as a prognostic marker for certain cancers. The encoded protein may play a role in regulating p53-mediated apoptosis. [provided by RefSeq, Sep 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.