Anti-XPR1/ IBGC6/ SLC53A1 monoclonal antibody

Anti-XPR1/ IBGC6/ SLC53A1 antibody for FACS & in-vivo assay

Target products collectionGo to XPR1/XPR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1950-Ab-1/ GM-Tg-hg-MP1950-Ab-2Anti-Human XPR1 monoclonal antibodyHuman
GM-Tg-rg-MP1950-Ab-1/ GM-Tg-rg-MP1950-Ab-2Anti-Rat XPR1 monoclonal antibodyRat
GM-Tg-mg-MP1950-Ab-1/ GM-Tg-mg-MP1950-Ab-2Anti-Mouse XPR1 monoclonal antibodyMouse
GM-Tg-cynog-MP1950-Ab-1/ GM-Tg-cynog-MP1950-Ab-2Anti-Cynomolgus/ Rhesus macaque XPR1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1950-Ab-1/ GM-Tg-felg-MP1950-Ab-2Anti-Feline XPR1 monoclonal antibodyFeline
GM-Tg-cang-MP1950-Ab-1/ GM-Tg-cang-MP1950-Ab-2Anti-Canine XPR1 monoclonal antibodyCanine
GM-Tg-bovg-MP1950-Ab-1/ GM-Tg-bovg-MP1950-Ab-2Anti-Bovine XPR1 monoclonal antibodyBovine
GM-Tg-equg-MP1950-Ab-1/ GM-Tg-equg-MP1950-Ab-2Anti-Equine XPR1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1950-Ab-1/ GM-Tg-hg-MP1950-Ab-2; GM-Tg-rg-MP1950-Ab-1/ GM-Tg-rg-MP1950-Ab-2;
GM-Tg-mg-MP1950-Ab-1/ GM-Tg-mg-MP1950-Ab-2; GM-Tg-cynog-MP1950-Ab-1/ GM-Tg-cynog-MP1950-Ab-2;
GM-Tg-felg-MP1950-Ab-1/ GM-Tg-felg-MP1950-Ab-2; GM-Tg-cang-MP1950-Ab-1/ GM-Tg-cang-MP1950-Ab-2;
GM-Tg-bovg-MP1950-Ab-1/ GM-Tg-bovg-MP1950-Ab-2; GM-Tg-equg-MP1950-Ab-1/ GM-Tg-equg-MP1950-Ab-2
Products NameAnti-XPR1 monoclonal antibody
Formatmab
Target NameXPR1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-XPR1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species XPR1/ IBGC6/ SLC53A1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm003664mouse Xpr1 Lentivirus plasmid
    ORF Viral VectorvGMLPm003664mouse Xpr1 Lentivirus particle


    Target information

    Target IDGM-MP1950
    Target NameXPR1
    Gene ID9213,19775,289424,716337,490301,100505400,536550,100051159
    Gene Symbol and SynonymsIBGC6,Rmc-1,Rmc1,SLC53A1,Sxv,SYG1,X3,XPR1,XR
    Uniprot AccessionQ9UBH6
    Uniprot Entry NameXPR1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000143324
    Target ClassificationN/A

    The target: XPR1, gene name: XPR1, also named as IBGC6, SLC53A1, SYG1, X3. The protein encoded by this gene is a receptor for the xenotropic and polytropic classes of murine leukemia viruses. The encoded protein is involved in phosphate homeostasis by mediating phosphate export from the cell. Defects in this gene have been associated with idiopathic basal ganglia calcification-6. [provided by RefSeq, Jun 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.