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Anti-WNT6 monoclonal antibody
Anti-WNT6 antibody for FACS & in-vivo assay
Go to WNT6/WNT6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1938-Ab-1/ GM-Tg-hg-MP1938-Ab-2 | Anti-Human WNT6 monoclonal antibody | Human |
| GM-Tg-rg-MP1938-Ab-1/ GM-Tg-rg-MP1938-Ab-2 | Anti-Rat WNT6 monoclonal antibody | Rat |
| GM-Tg-mg-MP1938-Ab-1/ GM-Tg-mg-MP1938-Ab-2 | Anti-Mouse WNT6 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1938-Ab-1/ GM-Tg-cynog-MP1938-Ab-2 | Anti-Cynomolgus/ Rhesus macaque WNT6 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1938-Ab-1/ GM-Tg-felg-MP1938-Ab-2 | Anti-Feline WNT6 monoclonal antibody | Feline |
| GM-Tg-cang-MP1938-Ab-1/ GM-Tg-cang-MP1938-Ab-2 | Anti-Canine WNT6 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1938-Ab-1/ GM-Tg-bovg-MP1938-Ab-2 | Anti-Bovine WNT6 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1938-Ab-1/ GM-Tg-equg-MP1938-Ab-2 | Anti-Equine WNT6 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1938-Ab-1/ GM-Tg-hg-MP1938-Ab-2; GM-Tg-rg-MP1938-Ab-1/ GM-Tg-rg-MP1938-Ab-2; GM-Tg-mg-MP1938-Ab-1/ GM-Tg-mg-MP1938-Ab-2; GM-Tg-cynog-MP1938-Ab-1/ GM-Tg-cynog-MP1938-Ab-2; GM-Tg-felg-MP1938-Ab-1/ GM-Tg-felg-MP1938-Ab-2; GM-Tg-cang-MP1938-Ab-1/ GM-Tg-cang-MP1938-Ab-2; GM-Tg-bovg-MP1938-Ab-1/ GM-Tg-bovg-MP1938-Ab-2; GM-Tg-equg-MP1938-Ab-1/ GM-Tg-equg-MP1938-Ab-2 |
| Products Name | Anti-WNT6 monoclonal antibody |
| Format | mab |
| Target Name | WNT6 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-WNT6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species WNT6 VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-MP1938-Ag-1 | wingless-type MMTV integration site family, member 6 (WNT6) protein |
| ORF Viral Vector | pGMLP002886 | human WNT6 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002886 | human WNT6 Lentivirus particle |
| ORF Viral Vector | pGMAD000530 | house mouse Wnt6 Adenovirus plasmid |
| ORF Viral Vector | pGMLPm005160 | mouse Wnt6 Lentivirus plasmid |
| ORF Viral Vector | vGMAD000530 | house mouse Wnt6 Adenovirus particle |
| ORF Viral Vector | vGMLPm005160 | mouse Wnt6 Lentivirus particle |
Target information
| Target ID | GM-MP1938 |
| Target Name | WNT6 |
| Gene ID | 7475,22420,316526,700573,488527,101099392,505075,100058824 |
| Gene Symbol and Synonyms | Wnt-6,WNT6 |
| Uniprot Accession | Q9Y6F9 |
| Uniprot Entry Name | WNT6_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000115596 |
| Target Classification | N/A |
The target: WNT6, gene name: WNT6, also named as . The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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