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Anti-VANG2/ VANGL2/ LPP1 monoclonal antibody
Anti-VANG2/ VANGL2/ LPP1 antibody for FACS & in-vivo assay
Go to VANGL2/VANGL2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1916-Ab-1/ GM-Tg-hg-MP1916-Ab-2 | Anti-Human VANGL2 monoclonal antibody | Human |
| GM-Tg-rg-MP1916-Ab-1/ GM-Tg-rg-MP1916-Ab-2 | Anti-Rat VANGL2 monoclonal antibody | Rat |
| GM-Tg-mg-MP1916-Ab-1/ GM-Tg-mg-MP1916-Ab-2 | Anti-Mouse VANGL2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1916-Ab-1/ GM-Tg-cynog-MP1916-Ab-2 | Anti-Cynomolgus/ Rhesus macaque VANGL2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1916-Ab-1/ GM-Tg-felg-MP1916-Ab-2 | Anti-Feline VANGL2 monoclonal antibody | Feline |
| GM-Tg-cang-MP1916-Ab-1/ GM-Tg-cang-MP1916-Ab-2 | Anti-Canine VANGL2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1916-Ab-1/ GM-Tg-bovg-MP1916-Ab-2 | Anti-Bovine VANGL2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1916-Ab-1/ GM-Tg-equg-MP1916-Ab-2 | Anti-Equine VANGL2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1916-Ab-1/ GM-Tg-hg-MP1916-Ab-2; GM-Tg-rg-MP1916-Ab-1/ GM-Tg-rg-MP1916-Ab-2; GM-Tg-mg-MP1916-Ab-1/ GM-Tg-mg-MP1916-Ab-2; GM-Tg-cynog-MP1916-Ab-1/ GM-Tg-cynog-MP1916-Ab-2; GM-Tg-felg-MP1916-Ab-1/ GM-Tg-felg-MP1916-Ab-2; GM-Tg-cang-MP1916-Ab-1/ GM-Tg-cang-MP1916-Ab-2; GM-Tg-bovg-MP1916-Ab-1/ GM-Tg-bovg-MP1916-Ab-2; GM-Tg-equg-MP1916-Ab-1/ GM-Tg-equg-MP1916-Ab-2 |
| Products Name | Anti-VANGL2 monoclonal antibody |
| Format | mab |
| Target Name | VANGL2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-VANGL2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species VANG2/ VANGL2/ LPP1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP001083 | human VANGL2 Lentivirus particle |
| ORF Viral Vector | pGMLP001083 | human VANGL2 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000539 | human VANGL2 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000539 | human VANGL2 Lentivirus particle |
| ORF Viral Vector | pGMLPm003450 | mouse Vangl2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003450 | mouse Vangl2 Lentivirus particle |
Target information
| Target ID | GM-MP1916 |
| Target Name | VANGL2 |
| Gene ID | 57216,93840,289229,720239,610037,101094645,520544,100053765 |
| Gene Symbol and Synonyms | C530001F03Rik,loop-tail,Lootl,Lp,LPP1,LTAP,ska17,ska |
| Uniprot Accession | Q9ULK5,P84889 |
| Uniprot Entry Name | VANG2_HUMAN,VANG2_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000162738 |
| Target Classification | N/A |
The target: VANGL2, gene name: VANGL2, also named as LPP1, LTAP, STB1, STBM, STBM1. The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate. [provided by RefSeq, Sep 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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