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Anti-VAMP7/ SYBL1/ TI-VAMP monoclonal antibody
Anti-VAMP7/ SYBL1/ TI-VAMP antibody for FACS & in-vivo assay
Go to VAMP7/VAMP7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1914-Ab-1/ GM-Tg-hg-MP1914-Ab-2 | Anti-Human VAMP7 monoclonal antibody | Human |
| GM-Tg-rg-MP1914-Ab-1/ GM-Tg-rg-MP1914-Ab-2 | Anti-Rat VAMP7 monoclonal antibody | Rat |
| GM-Tg-mg-MP1914-Ab-1/ GM-Tg-mg-MP1914-Ab-2 | Anti-Mouse VAMP7 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1914-Ab-1/ GM-Tg-cynog-MP1914-Ab-2 | Anti-Cynomolgus/ Rhesus macaque VAMP7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1914-Ab-1/ GM-Tg-felg-MP1914-Ab-2 | Anti-Feline VAMP7 monoclonal antibody | Feline |
| GM-Tg-cang-MP1914-Ab-1/ GM-Tg-cang-MP1914-Ab-2 | Anti-Canine VAMP7 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1914-Ab-1/ GM-Tg-bovg-MP1914-Ab-2 | Anti-Bovine VAMP7 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1914-Ab-1/ GM-Tg-equg-MP1914-Ab-2 | Anti-Equine VAMP7 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1914-Ab-1/ GM-Tg-hg-MP1914-Ab-2; GM-Tg-rg-MP1914-Ab-1/ GM-Tg-rg-MP1914-Ab-2; GM-Tg-mg-MP1914-Ab-1/ GM-Tg-mg-MP1914-Ab-2; GM-Tg-cynog-MP1914-Ab-1/ GM-Tg-cynog-MP1914-Ab-2; GM-Tg-felg-MP1914-Ab-1/ GM-Tg-felg-MP1914-Ab-2; GM-Tg-cang-MP1914-Ab-1/ GM-Tg-cang-MP1914-Ab-2; GM-Tg-bovg-MP1914-Ab-1/ GM-Tg-bovg-MP1914-Ab-2; GM-Tg-equg-MP1914-Ab-1/ GM-Tg-equg-MP1914-Ab-2 |
| Products Name | Anti-VAMP7 monoclonal antibody |
| Format | mab |
| Target Name | VAMP7 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-VAMP7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species VAMP7/ SYBL1/ TI-VAMP VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP000809 | human VAMP7 Lentivirus particle |
| ORF Viral Vector | pGMLP000809 | human VAMP7 Lentivirus plasmid |
| ORF Viral Vector | pGMAD000519 | house mouse Vamp7 Adenovirus plasmid |
| ORF Viral Vector | pGMLPm000511 | mouse Vamp7 Lentivirus plasmid |
| ORF Viral Vector | vGMAD000519 | house mouse Vamp7 Adenovirus particle |
| ORF Viral Vector | vGMLPm000511 | mouse Vamp7 Lentivirus particle |
Target information
| Target ID | GM-MP1914 |
| Target Name | VAMP7 |
| Gene ID | 6845,20955,85491,704160,612663,101095160,613984,100062131 |
| Gene Symbol and Synonyms | SYBL1,TI-VAMP,TIVAMP,VAMP-7,VAMP7 |
| Uniprot Accession | P51809,Q9JHW5,Q17QI5 |
| Uniprot Entry Name | VAMP7_HUMAN,VAMP7_RAT,VAMP7_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000124333 |
| Target Classification | N/A |
The target: VAMP7, gene name: VAMP7, also named as SYBL1, TI-VAMP, TIVAMP, VAMP-7. This gene encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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