Anti-VAMP3/ CEB monoclonal antibody

Anti-VAMP3/ CEB antibody for FACS & in-vivo assay

Target products collectionGo to VAMP3/VAMP3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1911-Ab-1/ GM-Tg-hg-MP1911-Ab-2Anti-Human VAMP3 monoclonal antibodyHuman
GM-Tg-rg-MP1911-Ab-1/ GM-Tg-rg-MP1911-Ab-2Anti-Rat VAMP3 monoclonal antibodyRat
GM-Tg-mg-MP1911-Ab-1/ GM-Tg-mg-MP1911-Ab-2Anti-Mouse VAMP3 monoclonal antibodyMouse
GM-Tg-cynog-MP1911-Ab-1/ GM-Tg-cynog-MP1911-Ab-2Anti-Cynomolgus/ Rhesus macaque VAMP3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1911-Ab-1/ GM-Tg-felg-MP1911-Ab-2Anti-Feline VAMP3 monoclonal antibodyFeline
GM-Tg-cang-MP1911-Ab-1/ GM-Tg-cang-MP1911-Ab-2Anti-Canine VAMP3 monoclonal antibodyCanine
GM-Tg-bovg-MP1911-Ab-1/ GM-Tg-bovg-MP1911-Ab-2Anti-Bovine VAMP3 monoclonal antibodyBovine
GM-Tg-equg-MP1911-Ab-1/ GM-Tg-equg-MP1911-Ab-2Anti-Equine VAMP3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1911-Ab-1/ GM-Tg-hg-MP1911-Ab-2; GM-Tg-rg-MP1911-Ab-1/ GM-Tg-rg-MP1911-Ab-2;
GM-Tg-mg-MP1911-Ab-1/ GM-Tg-mg-MP1911-Ab-2; GM-Tg-cynog-MP1911-Ab-1/ GM-Tg-cynog-MP1911-Ab-2;
GM-Tg-felg-MP1911-Ab-1/ GM-Tg-felg-MP1911-Ab-2; GM-Tg-cang-MP1911-Ab-1/ GM-Tg-cang-MP1911-Ab-2;
GM-Tg-bovg-MP1911-Ab-1/ GM-Tg-bovg-MP1911-Ab-2; GM-Tg-equg-MP1911-Ab-1/ GM-Tg-equg-MP1911-Ab-2
Products NameAnti-VAMP3 monoclonal antibody
Formatmab
Target NameVAMP3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-VAMP3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species VAMP3/ CEB VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1911
    Target NameVAMP3
    Gene ID9341,22319,29528,707972,102154970,101095593,505379,100630321
    Gene Symbol and SynonymsCEB,D130027G05Rik,VAMP-3,VAMP3
    Uniprot AccessionQ15836,P63025,Q2KJD2
    Uniprot Entry NameVAMP3_HUMAN,VAMP3_RAT,VAMP3_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000049245
    Target ClassificationN/A

    The target: VAMP3, gene name: VAMP3, also named as CEB. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.