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Anti-UPK3A/ UP3A/ UPIII monoclonal antibody
Anti-UPK3A/ UP3A/ UPIII antibody for FACS & in-vivo assay
Go to UPK3A/UPK3A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1908-Ab-1/ GM-Tg-hg-MP1908-Ab-2 | Anti-Human UPK3A monoclonal antibody | Human |
| GM-Tg-rg-MP1908-Ab-1/ GM-Tg-rg-MP1908-Ab-2 | Anti-Rat UPK3A monoclonal antibody | Rat |
| GM-Tg-mg-MP1908-Ab-1/ GM-Tg-mg-MP1908-Ab-2 | Anti-Mouse UPK3A monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1908-Ab-1/ GM-Tg-cynog-MP1908-Ab-2 | Anti-Cynomolgus/ Rhesus macaque UPK3A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1908-Ab-1/ GM-Tg-felg-MP1908-Ab-2 | Anti-Feline UPK3A monoclonal antibody | Feline |
| GM-Tg-cang-MP1908-Ab-1/ GM-Tg-cang-MP1908-Ab-2 | Anti-Canine UPK3A monoclonal antibody | Canine |
| GM-Tg-bovg-MP1908-Ab-1/ GM-Tg-bovg-MP1908-Ab-2 | Anti-Bovine UPK3A monoclonal antibody | Bovine |
| GM-Tg-equg-MP1908-Ab-1/ GM-Tg-equg-MP1908-Ab-2 | Anti-Equine UPK3A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1908-Ab-1/ GM-Tg-hg-MP1908-Ab-2; GM-Tg-rg-MP1908-Ab-1/ GM-Tg-rg-MP1908-Ab-2; GM-Tg-mg-MP1908-Ab-1/ GM-Tg-mg-MP1908-Ab-2; GM-Tg-cynog-MP1908-Ab-1/ GM-Tg-cynog-MP1908-Ab-2; GM-Tg-felg-MP1908-Ab-1/ GM-Tg-felg-MP1908-Ab-2; GM-Tg-cang-MP1908-Ab-1/ GM-Tg-cang-MP1908-Ab-2; GM-Tg-bovg-MP1908-Ab-1/ GM-Tg-bovg-MP1908-Ab-2; GM-Tg-equg-MP1908-Ab-1/ GM-Tg-equg-MP1908-Ab-2 |
| Products Name | Anti-UPK3A monoclonal antibody |
| Format | mab |
| Target Name | UPK3A |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-UPK3A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species UPK3A/ UP3A/ UPIII VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP004984 | human UPK3A Lentivirus particle |
| ORF Viral Vector | pGMLP004984 | human UPK3A Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001933 | mouse Upk3a Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001933 | mouse Upk3a Lentivirus particle |
Target information
| Target ID | GM-MP1908 |
| Target Name | UPK3A |
| Gene ID | 7380,22270,315190,717456,609118,101088858,100336102,100052016 |
| Gene Symbol and Synonyms | 1110017C07Rik,UP3A,UPIII,UPIIIA,UPK3,UPK3A |
| Uniprot Accession | O75631,P38574 |
| Uniprot Entry Name | UPK3A_HUMAN,UPK3A_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Malignant neoplasm of bladder |
| Gene Ensembl | ENSG00000100373 |
| Target Classification | N/A |
The target: UPK3A, gene name: UPK3A, also named as UP3A, UPIII, UPIIIA, UPK3. This gene encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the apical surface of the bladder epithelium. Mutations in this gene may be associated with renal adysplasia. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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