Anti-TIMD4/ SMUCKLER/ TIM4 monoclonal antibody

Anti-TIMD4/ SMUCKLER/ TIM4 antibody for FACS & in-vivo assay

Target products collectionGo to TIMD4/TIMD4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1798-Ab-1/ GM-Tg-hg-MP1798-Ab-2Anti-Human TIMD4 monoclonal antibodyHuman
GM-Tg-rg-MP1798-Ab-1/ GM-Tg-rg-MP1798-Ab-2Anti-Rat TIMD4 monoclonal antibodyRat
GM-Tg-mg-MP1798-Ab-1/ GM-Tg-mg-MP1798-Ab-2Anti-Mouse TIMD4 monoclonal antibodyMouse
GM-Tg-cynog-MP1798-Ab-1/ GM-Tg-cynog-MP1798-Ab-2Anti-Cynomolgus/ Rhesus macaque TIMD4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1798-Ab-1/ GM-Tg-felg-MP1798-Ab-2Anti-Feline TIMD4 monoclonal antibodyFeline
GM-Tg-cang-MP1798-Ab-1/ GM-Tg-cang-MP1798-Ab-2Anti-Canine TIMD4 monoclonal antibodyCanine
GM-Tg-bovg-MP1798-Ab-1/ GM-Tg-bovg-MP1798-Ab-2Anti-Bovine TIMD4 monoclonal antibodyBovine
GM-Tg-equg-MP1798-Ab-1/ GM-Tg-equg-MP1798-Ab-2Anti-Equine TIMD4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1798-Ab-1/ GM-Tg-hg-MP1798-Ab-2; GM-Tg-rg-MP1798-Ab-1/ GM-Tg-rg-MP1798-Ab-2;
GM-Tg-mg-MP1798-Ab-1/ GM-Tg-mg-MP1798-Ab-2; GM-Tg-cynog-MP1798-Ab-1/ GM-Tg-cynog-MP1798-Ab-2;
GM-Tg-felg-MP1798-Ab-1/ GM-Tg-felg-MP1798-Ab-2; GM-Tg-cang-MP1798-Ab-1/ GM-Tg-cang-MP1798-Ab-2;
GM-Tg-bovg-MP1798-Ab-1/ GM-Tg-bovg-MP1798-Ab-2; GM-Tg-equg-MP1798-Ab-1/ GM-Tg-equg-MP1798-Ab-2
Products NameAnti-TIMD4 monoclonal antibody
Formatmab
Target NameTIMD4
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TIMD4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TIMD4/ SMUCKLER/ TIM4 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm003797mouse Timd4 Lentivirus plasmid
    ORF Viral VectorvGMLPm003797mouse Timd4 Lentivirus particle


    Target information

    Target IDGM-MP1798
    Target NameTIMD4
    Gene ID91937,715236,489160,102901239,100630177
    Gene Symbol and SynonymsSMUCKLER,TIM4,TIMD4
    Uniprot AccessionQ96H15
    Uniprot Entry NameTIMD4_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000145850
    Target ClassificationN/A

    The target: TIMD4, gene name: TIMD4, also named as SMUCKLER, TIM4. Predicted to enable phosphatidylserine binding activity. Predicted to act upstream of or within apoptotic cell clearance. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.