Anti-TA2R4/ TAS2R4/ T2R4 monoclonal antibody

Anti-TA2R4/ TAS2R4/ T2R4 antibody for FACS & in-vivo assay

Target products collectionGo to TAS2R4/TAS2R4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1771-Ab-1/ GM-Tg-hg-MP1771-Ab-2Anti-Human TAS2R4 monoclonal antibodyHuman
GM-Tg-rg-MP1771-Ab-1/ GM-Tg-rg-MP1771-Ab-2Anti-Rat TAS2R4 monoclonal antibodyRat
GM-Tg-mg-MP1771-Ab-1/ GM-Tg-mg-MP1771-Ab-2Anti-Mouse TAS2R4 monoclonal antibodyMouse
GM-Tg-cynog-MP1771-Ab-1/ GM-Tg-cynog-MP1771-Ab-2Anti-Cynomolgus/ Rhesus macaque TAS2R4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1771-Ab-1/ GM-Tg-felg-MP1771-Ab-2Anti-Feline TAS2R4 monoclonal antibodyFeline
GM-Tg-cang-MP1771-Ab-1/ GM-Tg-cang-MP1771-Ab-2Anti-Canine TAS2R4 monoclonal antibodyCanine
GM-Tg-bovg-MP1771-Ab-1/ GM-Tg-bovg-MP1771-Ab-2Anti-Bovine TAS2R4 monoclonal antibodyBovine
GM-Tg-equg-MP1771-Ab-1/ GM-Tg-equg-MP1771-Ab-2Anti-Equine TAS2R4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1771-Ab-1/ GM-Tg-hg-MP1771-Ab-2; GM-Tg-rg-MP1771-Ab-1/ GM-Tg-rg-MP1771-Ab-2;
GM-Tg-mg-MP1771-Ab-1/ GM-Tg-mg-MP1771-Ab-2; GM-Tg-cynog-MP1771-Ab-1/ GM-Tg-cynog-MP1771-Ab-2;
GM-Tg-felg-MP1771-Ab-1/ GM-Tg-felg-MP1771-Ab-2; GM-Tg-cang-MP1771-Ab-1/ GM-Tg-cang-MP1771-Ab-2;
GM-Tg-bovg-MP1771-Ab-1/ GM-Tg-bovg-MP1771-Ab-2; GM-Tg-equg-MP1771-Ab-1/ GM-Tg-equg-MP1771-Ab-2
Products NameAnti-TAS2R4 monoclonal antibody
Formatmab
Target NameTAS2R4
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TAS2R4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TA2R4/ TAS2R4/ T2R4 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1771
    Target NameTAS2R4
    Gene ID50832,57253,554302,694737,100688996,105260396,664648,100146597
    Gene Symbol and SynonymsMamu-T2R4,mGR08,mt2r8,T2R108,T2R16,T2R4,T2r8,Tas2r108,TAS2R4,Tas2r8
    Uniprot AccessionQ9NYW5,Q67ET0
    Uniprot Entry NameTA2R4_HUMAN,TA2R4_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000127364
    Target ClassificationGPCR

    The target: TAS2R4, gene name: TAS2R4, also named as T2R4. This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.