Anti-T2R20/ TAS2R20/ T2R49 monoclonal antibody

Anti-T2R20/ TAS2R20/ T2R49 antibody for FACS & in-vivo assay

Target products collectionGo to TAS2R20/TAS2R20 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1764-Ab-1/ GM-Tg-hg-MP1764-Ab-2Anti-Human TAS2R20 monoclonal antibodyHuman
GM-Tg-rg-MP1764-Ab-1/ GM-Tg-rg-MP1764-Ab-2Anti-Rat TAS2R20 monoclonal antibodyRat
GM-Tg-mg-MP1764-Ab-1/ GM-Tg-mg-MP1764-Ab-2Anti-Mouse TAS2R20 monoclonal antibodyMouse
GM-Tg-cynog-MP1764-Ab-1/ GM-Tg-cynog-MP1764-Ab-2Anti-Cynomolgus/ Rhesus macaque TAS2R20 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1764-Ab-1/ GM-Tg-felg-MP1764-Ab-2Anti-Feline TAS2R20 monoclonal antibodyFeline
GM-Tg-cang-MP1764-Ab-1/ GM-Tg-cang-MP1764-Ab-2Anti-Canine TAS2R20 monoclonal antibodyCanine
GM-Tg-bovg-MP1764-Ab-1/ GM-Tg-bovg-MP1764-Ab-2Anti-Bovine TAS2R20 monoclonal antibodyBovine
GM-Tg-equg-MP1764-Ab-1/ GM-Tg-equg-MP1764-Ab-2Anti-Equine TAS2R20 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1764-Ab-1/ GM-Tg-hg-MP1764-Ab-2; GM-Tg-rg-MP1764-Ab-1/ GM-Tg-rg-MP1764-Ab-2;
GM-Tg-mg-MP1764-Ab-1/ GM-Tg-mg-MP1764-Ab-2; GM-Tg-cynog-MP1764-Ab-1/ GM-Tg-cynog-MP1764-Ab-2;
GM-Tg-felg-MP1764-Ab-1/ GM-Tg-felg-MP1764-Ab-2; GM-Tg-cang-MP1764-Ab-1/ GM-Tg-cang-MP1764-Ab-2;
GM-Tg-bovg-MP1764-Ab-1/ GM-Tg-bovg-MP1764-Ab-2; GM-Tg-equg-MP1764-Ab-1/ GM-Tg-equg-MP1764-Ab-2
Products NameAnti-TAS2R20 monoclonal antibody
Formatmab
Target NameTAS2R20
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TAS2R20 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species T2R20/ TAS2R20/ T2R49 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1764
    Target NameTAS2R20
    Gene ID259295
    Gene Symbol and SynonymsT2R20,T2R49,T2R56,TAS2R20,TAS2R49
    Uniprot AccessionP59543
    Uniprot Entry NameT2R20_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000255837
    Target ClassificationGPCR

    The target: TAS2R20, gene name: TAS2R20, also named as T2R20, T2R49, T2R56, TAS2R49. This gene encodes a member of the taste receptor two family of class C G-protein coupled receptors. Receptors of this family have a short extracellular N-terminus, seven transmembrane helices, three extracellular loops and three intracellular loops, and an intracellular C-terminus. Members of this family are expressed in a subset of taste receptor cells, where they function in bitter taste reception, as well as in non-gustatory cells including those of the brain, reproductive organs, respiratory system, and gastrointestinal system. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.