Anti-TAAR6/ TA4/ TAR4 monoclonal antibody

Anti-TAAR6/ TA4/ TAR4 antibody for FACS & in-vivo assay

Target products collectionGo to TAAR6/TAAR6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1753-Ab-1/ GM-Tg-hg-MP1753-Ab-2Anti-Human TAAR6 monoclonal antibodyHuman
GM-Tg-rg-MP1753-Ab-1/ GM-Tg-rg-MP1753-Ab-2Anti-Rat TAAR6 monoclonal antibodyRat
GM-Tg-mg-MP1753-Ab-1/ GM-Tg-mg-MP1753-Ab-2Anti-Mouse TAAR6 monoclonal antibodyMouse
GM-Tg-cynog-MP1753-Ab-1/ GM-Tg-cynog-MP1753-Ab-2Anti-Cynomolgus/ Rhesus macaque TAAR6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1753-Ab-1/ GM-Tg-felg-MP1753-Ab-2Anti-Feline TAAR6 monoclonal antibodyFeline
GM-Tg-cang-MP1753-Ab-1/ GM-Tg-cang-MP1753-Ab-2Anti-Canine TAAR6 monoclonal antibodyCanine
GM-Tg-bovg-MP1753-Ab-1/ GM-Tg-bovg-MP1753-Ab-2Anti-Bovine TAAR6 monoclonal antibodyBovine
GM-Tg-equg-MP1753-Ab-1/ GM-Tg-equg-MP1753-Ab-2Anti-Equine TAAR6 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1753-Ab-1/ GM-Tg-hg-MP1753-Ab-2; GM-Tg-rg-MP1753-Ab-1/ GM-Tg-rg-MP1753-Ab-2;
GM-Tg-mg-MP1753-Ab-1/ GM-Tg-mg-MP1753-Ab-2; GM-Tg-cynog-MP1753-Ab-1/ GM-Tg-cynog-MP1753-Ab-2;
GM-Tg-felg-MP1753-Ab-1/ GM-Tg-felg-MP1753-Ab-2; GM-Tg-cang-MP1753-Ab-1/ GM-Tg-cang-MP1753-Ab-2;
GM-Tg-bovg-MP1753-Ab-1/ GM-Tg-bovg-MP1753-Ab-2; GM-Tg-equg-MP1753-Ab-1/ GM-Tg-equg-MP1753-Ab-2
Products NameAnti-TAAR6 monoclonal antibody
Formatmab
Target NameTAAR6
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TAAR6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TAAR6/ TA4/ TAR4 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1753
    Target NameTAAR6
    Gene ID319100,215855,709418
    Gene Symbol and SynonymsGm228,TA4,TAAR6,taR-4,taR-6,TAR4,TAR6,TRAR4
    Uniprot AccessionQ96RI8
    Uniprot Entry NameTAAR6_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000146383
    Target ClassificationN/A

    The target: TAAR6, gene name: TAAR6, also named as TA4, TAR4, TAR6, TRAR4, taR-4, taR-6. This gene encodes a seven-transmembrane G-protein-coupled receptor that likely functions as a receptor for endogenous trace amines. Mutations in this gene may be associated with schizophrenia.[provided by RefSeq, Feb 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.