Anti-YLAT1/ SLC7A7/ LAT3 monoclonal antibody
Anti-YLAT1/ SLC7A7/ LAT3 antibody for FACS & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-MP1666-Ab-1/ GM-Tg-hg-MP1666-Ab-2 | Anti-Human SLC7A7 monoclonal antibody | Human |
GM-Tg-rg-MP1666-Ab-1/ GM-Tg-rg-MP1666-Ab-2 | Anti-Rat SLC7A7 monoclonal antibody | Rat |
GM-Tg-mg-MP1666-Ab-1/ GM-Tg-mg-MP1666-Ab-2 | Anti-Mouse SLC7A7 monoclonal antibody | Mouse |
GM-Tg-cynog-MP1666-Ab-1/ GM-Tg-cynog-MP1666-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC7A7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-MP1666-Ab-1/ GM-Tg-felg-MP1666-Ab-2 | Anti-Feline SLC7A7 monoclonal antibody | Feline |
GM-Tg-cang-MP1666-Ab-1/ GM-Tg-cang-MP1666-Ab-2 | Anti-Canine SLC7A7 monoclonal antibody | Canine |
GM-Tg-bovg-MP1666-Ab-1/ GM-Tg-bovg-MP1666-Ab-2 | Anti-Bovine SLC7A7 monoclonal antibody | Bovine |
GM-Tg-equg-MP1666-Ab-1/ GM-Tg-equg-MP1666-Ab-2 | Anti-Equine SLC7A7 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-MP1666-Ab-1/ GM-Tg-hg-MP1666-Ab-2; GM-Tg-rg-MP1666-Ab-1/ GM-Tg-rg-MP1666-Ab-2; GM-Tg-mg-MP1666-Ab-1/ GM-Tg-mg-MP1666-Ab-2; GM-Tg-cynog-MP1666-Ab-1/ GM-Tg-cynog-MP1666-Ab-2; GM-Tg-felg-MP1666-Ab-1/ GM-Tg-felg-MP1666-Ab-2; GM-Tg-cang-MP1666-Ab-1/ GM-Tg-cang-MP1666-Ab-2; GM-Tg-bovg-MP1666-Ab-1/ GM-Tg-bovg-MP1666-Ab-2; GM-Tg-equg-MP1666-Ab-1/ GM-Tg-equg-MP1666-Ab-2 |
Products Name | Anti-SLC7A7 monoclonal antibody |
Format | mab |
Target Name | SLC7A7 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-SLC7A7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species YLAT1/ SLC7A7/ LAT3 VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | vGMLV000396 | human SLC7A7 Lentivirus particle |
ORF Viral Vector | pGMLV000396 | human SLC7A7 Lentivirus plasmid |
ORF Viral Vector | pGMLPm005351 | mouse Slc7a7 Lentivirus plasmid |
ORF Viral Vector | vGMLPm005351 | mouse Slc7a7 Lentivirus particle |
Target information
Target ID | GM-MP1666 |
Target Name | SLC7A7 |
Gene ID | 9056,20540,83509,712466,490602,101089271,504220,106782083 |
Gene Symbol and Synonyms | LAT3,LPI,MOP-2,my+lat1,SLC7A7,y+LAT-1,Y+LAT1 |
Uniprot Accession | Q9UM01,Q9R0S5 |
Uniprot Entry Name | YLAT1_HUMAN,YLAT1_RAT |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000155465 |
Target Classification | N/A |
The target: SLC7A7, gene name: SLC7A7, also named as LAT3, LPI, MOP-2, Y+LAT1, y+LAT-1. The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.