Anti-CTR3/ SLC7A3/ ATRC3 monoclonal antibody

Anti-CTR3/ SLC7A3/ ATRC3 antibody for FACS & in-vivo assay

Target products collectionGo to SLC7A3/SLC7A3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1663-Ab-1/ GM-Tg-hg-MP1663-Ab-2Anti-Human SLC7A3 monoclonal antibodyHuman
GM-Tg-rg-MP1663-Ab-1/ GM-Tg-rg-MP1663-Ab-2Anti-Rat SLC7A3 monoclonal antibodyRat
GM-Tg-mg-MP1663-Ab-1/ GM-Tg-mg-MP1663-Ab-2Anti-Mouse SLC7A3 monoclonal antibodyMouse
GM-Tg-cynog-MP1663-Ab-1/ GM-Tg-cynog-MP1663-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC7A3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1663-Ab-1/ GM-Tg-felg-MP1663-Ab-2Anti-Feline SLC7A3 monoclonal antibodyFeline
GM-Tg-cang-MP1663-Ab-1/ GM-Tg-cang-MP1663-Ab-2Anti-Canine SLC7A3 monoclonal antibodyCanine
GM-Tg-bovg-MP1663-Ab-1/ GM-Tg-bovg-MP1663-Ab-2Anti-Bovine SLC7A3 monoclonal antibodyBovine
GM-Tg-equg-MP1663-Ab-1/ GM-Tg-equg-MP1663-Ab-2Anti-Equine SLC7A3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1663-Ab-1/ GM-Tg-hg-MP1663-Ab-2; GM-Tg-rg-MP1663-Ab-1/ GM-Tg-rg-MP1663-Ab-2;
GM-Tg-mg-MP1663-Ab-1/ GM-Tg-mg-MP1663-Ab-2; GM-Tg-cynog-MP1663-Ab-1/ GM-Tg-cynog-MP1663-Ab-2;
GM-Tg-felg-MP1663-Ab-1/ GM-Tg-felg-MP1663-Ab-2; GM-Tg-cang-MP1663-Ab-1/ GM-Tg-cang-MP1663-Ab-2;
GM-Tg-bovg-MP1663-Ab-1/ GM-Tg-bovg-MP1663-Ab-2; GM-Tg-equg-MP1663-Ab-1/ GM-Tg-equg-MP1663-Ab-2
Products NameAnti-SLC7A3 monoclonal antibody
Formatmab
Target NameSLC7A3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC7A3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CTR3/ SLC7A3/ ATRC3 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm003174mouse Slc7a3 Lentivirus plasmid
    ORF Viral VectorvGMLPm003174mouse Slc7a3 Lentivirus particle


    Target information

    Target IDGM-MP1663
    Target NameSLC7A3
    Gene ID84889,11989,29485,696288,491945,101089172,539065,100055782
    Gene Symbol and SynonymsATRC3,CAT-3,CAT3,SLC7A1,SLC7A2,SLC7A3
    Uniprot AccessionQ8WY07,O08812
    Uniprot Entry NameCTR3_HUMAN,CTR3_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000165349
    Target ClassificationN/A

    The target: SLC7A3, gene name: SLC7A3, also named as ATRC3, CAT-3, CAT3. This gene encodes a member of the solute carrier family 7. The encoded protein is a sodium-independent cationic amino acid transporter. Alternate splicing results in multiple transcripts that encoded the same protein.[provided by RefSeq, May 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.