Anti-S6A15/ SLC6A15/ NTT73 monoclonal antibody

Anti-S6A15/ SLC6A15/ NTT73 antibody for FACS & in-vivo assay

Target products collectionGo to SLC6A15/SLC6A15 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1655-Ab-1/ GM-Tg-hg-MP1655-Ab-2Anti-Human SLC6A15 monoclonal antibodyHuman
GM-Tg-rg-MP1655-Ab-1/ GM-Tg-rg-MP1655-Ab-2Anti-Rat SLC6A15 monoclonal antibodyRat
GM-Tg-mg-MP1655-Ab-1/ GM-Tg-mg-MP1655-Ab-2Anti-Mouse SLC6A15 monoclonal antibodyMouse
GM-Tg-cynog-MP1655-Ab-1/ GM-Tg-cynog-MP1655-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC6A15 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1655-Ab-1/ GM-Tg-felg-MP1655-Ab-2Anti-Feline SLC6A15 monoclonal antibodyFeline
GM-Tg-cang-MP1655-Ab-1/ GM-Tg-cang-MP1655-Ab-2Anti-Canine SLC6A15 monoclonal antibodyCanine
GM-Tg-bovg-MP1655-Ab-1/ GM-Tg-bovg-MP1655-Ab-2Anti-Bovine SLC6A15 monoclonal antibodyBovine
GM-Tg-equg-MP1655-Ab-1/ GM-Tg-equg-MP1655-Ab-2Anti-Equine SLC6A15 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1655-Ab-1/ GM-Tg-hg-MP1655-Ab-2; GM-Tg-rg-MP1655-Ab-1/ GM-Tg-rg-MP1655-Ab-2;
GM-Tg-mg-MP1655-Ab-1/ GM-Tg-mg-MP1655-Ab-2; GM-Tg-cynog-MP1655-Ab-1/ GM-Tg-cynog-MP1655-Ab-2;
GM-Tg-felg-MP1655-Ab-1/ GM-Tg-felg-MP1655-Ab-2; GM-Tg-cang-MP1655-Ab-1/ GM-Tg-cang-MP1655-Ab-2;
GM-Tg-bovg-MP1655-Ab-1/ GM-Tg-bovg-MP1655-Ab-2; GM-Tg-equg-MP1655-Ab-1/ GM-Tg-equg-MP1655-Ab-2
Products NameAnti-SLC6A15 monoclonal antibody
Formatmab
Target NameSLC6A15
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC6A15 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species S6A15/ SLC6A15/ NTT73 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1655
    Target NameSLC6A15
    Gene ID55117,103098,282712,698900,475416,101095111,281952,100050913
    Gene Symbol and Synonymshv7-3,NTT73,SBAT1,SLC6A15,V7-3
    Uniprot AccessionQ9H2J7,Q08469,Q9XS59
    Uniprot Entry NameS6A15_HUMAN,S6A15_RAT,S6A15_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000072041
    Target ClassificationN/A

    The target: SLC6A15, gene name: SLC6A15, also named as NTT73, SBAT1, V7-3, hv7-3. This gene encodes a member of the solute carrier family 6 protein family which transports neutral amino acids. The encoded protein is thought to play a role in neuronal amino acid transport (PMID: 16185194) and may be associated with major depression (PMID: 21521612). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.